Study title and authors:
Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatin.
Books: |
Downs JR, Clearfield M, Tyroler HA, Whitney EJ, Kruyer W, Langendorfer A, Zagrebelsky V, Weis S, Shapiro DR, Beere PA, Gotto AM.
Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, Texas, USA.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11348605
This study examined the effects of 20 to 40 mg/day of lovastatin in 6,605 generally healthy middle-aged and older men and women. 3,304 people received the statin drug and 3,301 people received a placebo.
The study found that the statin drug reduced the risk of a first acute major coronary event by 37%. However the statin drug also increased cancer rates by 41% and increased the overall death rate by 4%.
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Recipe of the day
Bacon wrapped roast beef with mustard and horseradish
Serves 4
Ingredients:
Food Mall: Sirloin Roast Beef |
•3 1/2 lb top sirloin roast beef;
•6 slices bacon;•¼ cup softened butter, clarified butter or other cooking fat;
•3 cloves garlic, minced;
•1 tbsp of Dijon or homemade mustard;
•1 tbsp good quality or homemade horseradish;
•3/4 cup red wine;
•1 3/4 cups homemade beef stock;
Preparation:
1.Preheat your oven to 400 F.
2.In a small bowl, combine the butter or other cooking fat, garlic, mustard and horseradish. Mix until smooth.
3.Rub the roast all over with the mixture.
4.Lay the bacon pieces out flat so that they are slightly overlapping. Then place the roast on top of the bacon and wrap the pieces around the roast. If needed, use toothpicks to hold the bacon in place.
5.Place the roast in a roasting dish and cook at 400 F for 20 minutes.
6.Once the roast has been in for 20 minutes, add the wine and stock to the roasting dish. At the same time, adjust the heat to 350 F.
7.Roast for about 70 minutes, depending on how well-done you like your meat. 20 minutes per pound is a good rule of thumb for a medium rare to medium well roast. There is a good reference chart included in the cookbook to know the exact roasting times of the different cuts of meat.
Bacon Wrapped Roast Beef with Mustard and Horseradish |
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