Rosuvastatin (Crestor) is associated with a 2.8-fold increased risk of lung cancer

This study was published in the Libyan Journal of Medicine 2012 Dec 27;7(0):1-3

 

Study title and authors:

Statins use and female lung cancer risk in Taiwan.

Lai SW, Liao KF, Lin CL, Sung FC, Cheng YH.

School of Medicine, China Medical University, Taichung, Taiwan; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23272648

This study investigated the assoiation between statins and lung cancer in women. The study included 1,117 women with newly diagnosed lung cancer, average age 66.5 years, who were compared to 4,468 age-matched women without lung cancer.

The study found:
(a) Statin use was associated with a 7% increased risk of lung cancer.
(b) Rosuvastatin (Crestor) use of over 12 months duration was associated with a 2.8-fold increased risk of lung cancer.

The data from the study reveals that statin use is associated with higher rates of lung cancer.

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In patients undergoing treatment for bladder cancer, statins are significantly associated with an increased risk of tumor progression

This study was published in the New England Journal of Medicine 2006 Dec 21;355(25):2705-7

 

Study title and authors:

Use of statins and outcome of BCG treatment for bladder cancer.

Hoffmann P, Roumeguère T, Schulman C, van Velthoven R.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17183004

This study investigated the association between statins and bladder cancer. The study, which lasted for 46 months, analyzed the clinical outcomes of 84 patients who had received the bacille Calmette–Guérin vaccine for the treatment of non–muscle-invasive bladder cancer.

The study found:
(a) In 53% of the patients who took statins, the tumor became more aggressive, whereas this change occurred in only 18% of the patients who did not take statins.
(b) 42% of the patients in the statin group had to undergo radical cystectomy, (radical cystectomy is the removal of the entire bladder, nearby lymph nodes, part of the urethra, and nearby organs that may contain cancer cells), as compared with only 14% of the patients who did not take statins.

In patients undergoing treatment for bladder cancer, the use of statins was significantly associated with an increased risk of tumor progression and a subsequent need for radical cystectomy.

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Statins are associated with higher death rates, higher cardiac death rates and increased risk of cancer

This study was published in Circulation 2000 Oct 10;102(15):1748-54

 

Study title and authors:

Long-term effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT).

Teo KK, Burton JR, Buller CE, Plante S, Catellier D, Tymchak W, Dzavik V, Taylor D, Yokoyama S, Montague TJ.

University of Alberta Hospitals, Edmonton, Alberta, Canada. teok@fhs.mcmaster.ca

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11023927

One of the aims of this long-term, multicenter, randomized, double-blind, placebo-controlled trial was to evaluate the effects of simvastatin in patients with normal cholesterol levels and with detectable plaque build up in at least three major coronary artery segments. The study lasted for four years and included  a total of 460 patients: 230 received simvastatin and 230, a placebo.

The study found:
(a) The patients receiving simvastatin had a 117% increased risk of death compared to the patients receiving placebo.
(b) The patients receiving simvastatin had a 76% increased risk of cardiac death compared to the patients receiving placebo.
(c) The patients receiving simvastatin had a 225% increased risk of non-cardiac death compared to the patients receiving placebo.
(d) The patients receiving simvastatin had a 9% increased risk of a heart attack compared to the patients receiving placebo.
(e) The patients receiving simvastatin had a 78% increased risk of cancer compared to the patients receiving placebo.

The data from the study reveals that statins are associated with higher death rates, higher cardiac death rates and increased risk of cancer. 

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Increased risk of breast cancer related to statin use

This study was published in Anticancer Research 2009 Dec;29(12):5143-8

Study title and authors:

Statins and breast cancer in postmenopausal women without hormone therapy.

Eaton M, Eklof J, Beal JR, Sahmoun AE.

University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20044629

This study investigated the association between statin use and risk of breast cancer among overweight or obese postmenopausal women who have never used hormone therapy. The study included 95 women with breast cancer and 94 controls. The women were aged from 55 to 81 years old and had a body mass index over 25.0 kg/m2.

The study found:
(a) Women who used statins had a 30% increased risk of breast cancer compared to women not using statins.
(b) Women who used lovastatin, simvastatin, fluvastatin, or atorvastatin type statins had a 310% increased risk of breast cancer.

This study found an increased risk of breast cancer related to statin use in overweight postmenopausal women.

Links to other studies:
Young women who are treated with statins may be at increased risk for the development of breast cancer
Statins may promote cancer in certain segments of the population

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NSAIDs and statins increase the risk of renal cell carcinoma

This study was presented at the American Urological Association Annual Meeting; May 19-23, 2012; Atlanta, GA. Abstract 575.

Study title and authors:
NSAID and statin use and risk of renal cell carcinoma.
Chéry L, Wright J, Hotaling J,

This study can be accessed at: http://www.onclive.com/publications/urologists-in-cancer-care/2012/June-2012/NSAIDs-and-Statins-Have-No-Impact-on-Renal-Cell-Carcinoma-Risk

Nonsteroidal anti-inflammatory drugs, or NSAIDs are the most prescribed medications for treating conditions such as arthritis. Examples of NSAIDs are aspirin, ibuprofen, naproxen and Nabumetone.

Chery notes that renal cell carcinoma, the most common type of kidney cancer, is the sixth most common cancer in men and the eighth most common cancer in women.

This study set out to determine the effect of NSAIDs and statins on the risk of renal cell carcinoma.  The study included 77,048 individuals aged 50 to 76 years

The study found:
(a) Those with a low use of NSAIDs (1-3 days/week or less than four years) had a 1% increased risk of developing renal cell carcinoma compared to nonusers of NSAIDs.
(b) Those with a high use of NSAIDs (more than four days/week and over four years) had a 20% increased risk of developing renal cell carcinoma compared to nonusers of NSAIDs.
(c) Those who were taking statins had a 10% increased risk of developing renal cell carcinoma.

The data from the study reveals that NSAIDs and statins increase the risk of renal cell carcinoma.

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Pravastatin increases the risk of cancer by 6%

This paper was published in the Canadian Medical Association Journal 2007 Feb 27;176(5):649-54

Study title and authors:

Does pravastatin promote cancer in elderly patients? A meta-analysis.

Bonovas S, Sitaras NM.

Department of Pharmacology, School of Medicine, University of Athens Athens, Greece. sbonovas@med.uoa.gr

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17325332

The aim of the study was to assess the effect of pravastatin therapy on cancer risk. The study analysed the results of 12 pravastatin trials which included 42,902 men and women, (21,454 patients in pravastatin groups and 21,448 in control groups).

The study found:
(a) Pravastatin users had a 6% increased risk of cancer compared to non-statin users.
(b) Pravastatin therapy was associated with an increasing risk of cancer as the patient age increased. E.g. The oldest pravastain users, aged over 75, had a 22% increased risk of cancer compared to non-users.

Bonovas concluded: "this analysis showed that pravastatin therapy was associated with an increasing risk of cancer as age increased".

Links to other studies:
Young women who are treated with statins may be at increased risk for the development of breast cancer
Statins increase cancer rates by 41% and the overall death rate by 4%
Statins increase the risk of prostate cancer

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Statin users have a 25% increased risk of developing Merkel cell carcinoma

This study was published in Cancer Epidemiology 2012 Jun 7

Study title and authors:

Increased incidence of Merkel cell carcinoma among younger statin users.

Sahi H, Koljonen V, Böhling T, Neuvonen PJ, Vainio H, Lamminpää A, Kyyrönen P, Pukkala E.

Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland; Department of Pathology, Helsinki University and HUSLAB, Helsinki, Finland.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22683172

Merkel cell carcinoma is a rare type of skin cancer. It develops in Merkel cells which are in the top layer of the skin.

The aim of the study was to find out whether statin users have an increased incidence of Merkel cell carcinoma. The study included 454,935 men and women.

The study found:
(a) Statin users had a 25% increased risk of developing Merkel cell carcinoma compared to non-statin users.
(b) Statin users aged under 60 had a 216% increased risk of developing Merkel cell carcinoma compared to non-statin users.

The study reveals that statin use is linked to higher rates of Merkel cell carcinoma.

Useful reading:
How Statin Drugs Really Lower Cholesterol: And Kill You One Cell at a Time

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Increase in colorectal cancer cases in statin users

This study was published in the World Journal of Gastroenterology 2011 Dec 21;17(47):5197-202

Study title and authors:
Statin use and the risk of colorectal cancer: a population-based case-control study.

Cheng MH, Chiu HF, Ho SC, Tsai SS, Wu TN, Yang CY.
Division of Pulmonary and Critical Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan, China.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22215945

The aim of the study was to investigate whether the use of statins is associated with colorectal cancer risk. The study included 1,156 colorectal cancer cases and 4,624 controls.

The results of the study revealed that those who were prescribed statins had a 9% increased risk of colorectal cancer compared to those who did not take statins.

Links to other studies:
Statins increase the risk of colon adenomas by 54%
Statins increase cancer rates by 41% and the overall death rate by 4%
Statins increase lymphoid malignancy rates by 124%

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Trend of increased kidney cancer risk with statins

This study was published in Expert Opinion on Drug Safety 2012 Apr 16

Study title and authors:
Statin use and the risk of kidney cancer: a population-based case-control study.

Chiu HF, Kuo CC, Kuo HW, Lee IM, Lee CT, Yang CY.
Kaohsiung Medical University, Institute of Pharmacology, College of Medicine , Kaohsiung , Taiwan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22502740

The objective of the study was to investigate whether the use of statins was associated with kidney cancer risk. The study included 177 kidney cancer cases and 708 controls aged 50 or over.

The study found that those who were prescribed statins had an 8% increased risk of kidney cancer compared to those that did not take statins.

The author of the paper, Professor Hui-Fen Chiu, advises; "there is a trend of increased kidney cancer risk" and "it is prudent to continue monitoring cancer incidence among long-standing statin users".

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Statin users have a 14% increased risk of melanoma

This study was published in Cancer 2012 Mar 20

Study title and authors:
Prospective analysis of association between use of statins and melanoma risk in the Women's Health Initiative.

Jagtap D, Rosenberg CA, Martin LW, Pettinger M, Khandekar J, Lane D, Ockene I, Simon MS.
Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22434400

Melanoma is the most lethal form of skin cancer. This study examined the association between statin use and the risk of melanoma. The study consisted of 119,726 postmenopausal white women who were followed for 11.6 years.

The study found that statin users had a 14% increased risk of melanoma compared to nonusers.

A research scientist notes that statins are also associated with a rise in non-melanoma skin cancer and liver cancer. See the article here.

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Statins increase the risk of prostate cancer by 55%

This study was published in Prostate 2011 Dec;71(16):1818-24

Study title and authors:
Statins increase the risk of prostate cancer: a population-based case-control study.

Chang CC, Ho SC, Chiu HF, Yang CY.
Department of Environmental and Occupational Health, National Cheng Kung University, Tainan, Taiwan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21480313

The aim of this study was to investigate whether the use of statins was associated with prostate cancer risk. The study included 388 prostate cancer cases and 1,552 controls. All patients were aged 50 years and older.

The study found that use of statins was associated with a 55% increase in prostate cancer risk.

See here to view an article by Dr Duane Graveline that explains how statins increase the risk of cancer.

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Statin treatment increases the risk of death from cancer

This study was published in the Journal of the American Medical Association 2002 Dec 18;288(23):2998-3007

Study title and authors:

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12479764

This study, which lasted for 6 years, was designed to determine whether pravastatin compared with patients usual medical care, reduces death rates in patients aged 55 or older who have high cholesterol and blood pressure and other heart disease risk factors. 10,355 participants were enrolled in the study and were assigned into 2 groups where they received either 40 mg of pravastatin a day or their usual medical care.

The researchers found at the end of the 6 year study:
(a) Heart disease death rates were virtually identical in both groups.
(b) Those who took statins had an 11% increased risk of death from cancer compared to those who did not take statins.
(c) Those who took statins had an 7% increased risk of suicide/homocide/accidental death compared to those who did not take statins.

The results of this study suggest that statin treatment increases the risk of death from cancer.

Links to other studies:
Statins may promote cancer in certain segments of the population
Statins raise prostate cancer risk of obese men
Young women who are treated with statins may be at increased risk for the development of breast cancer

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Low cholesterol increases cancer rates by 42%

This study was published in the Annals of Oncology 2009 Jun;20(6):1113-20

Study title and authors:

Time-dependent association of total serum cholesterol and cancer incidence in a cohort of 172,210 men and women: a prospective 19-year follow-up study.

Strasak AM, Pfeiffer RM, Brant LJ, Rapp K, Hilbe W, Oberaigner W, Lang S, Borena W, Concin H, Diem G, Ruttmann E, Glodny B, Pfeiffer KP, Ulmer H; VHM&PP Study Group.

Department of Medical Statistics, Informatics and Health Economics, Innsbruck Medical University, Innsbruck, Austria. alexander.strasak@i-med.ac.at

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19164459

The study investigated the association of cholesterol levels with subsequent cancer incidence in 172,210 Austrian adults who were followed for up to 19 years. 

The study found:
(a) Cancer rates in the men with the highest cholesterol (more than 235 mg/dL or 6.0 mmol/l) were up to 42% lower than the men with the lowest cholesterol.
(b) Cancer rates in the women with the highest cholesterol (more than 229 mg/dL or 5.9 mmol/l) were up to 31% lower than the women with the lowest cholesterol.

The study shows how low cholesterol is associated with increased cancer rates in men and women.

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Statins increase lymphoid malignancy rates by 124%

This study was published in Cancer Science 2006 Feb;97(2):133-8

Study title and authors:

Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.

Iwata H, Matsuo K, Hara S, Takeuchi K, Aoyama T, Murashige N, Kanda Y, Mori S, Suzuki R, Tachibana S, Yamane M, Odawara M, Mutou Y, Kami M.

Department of Cardiology, Toranomon Hospital, Tokyo 105-8470, Japan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16441424

The study examined the association between statin use and development of lymphoid malignancies. Statin use of 221 cases with proven lymphoid malignancies (lymphoma and myeloma), from Toranomon Hospital (Tokyo, Japan) was compared with statin use of 879 patients without malignancies from the same hospital.

The study found there was a 124% higher frequency of statin use among patients with lymphoid malignancies in comparison with the other patients.

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Statins offer no benefit to the elderly

This study was published in the Lancet 2002 Nov 23;360(9346):1623-30

Study title and authors:

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.

Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Meinders AE, Norrie J, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG; PROSPER study group. PROspective Study of Pravastatin in the Elderly at Risk.

University Department of Pathological Biochemistry, University of Glasgow, Royal Infirmary, Scotland, Glasgow, UK. jshepherd@gri-biochem.org.uk

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12457784

The aim of the trial was to ascertain the effects of pravastatin treatment in elderly men and women aged 70-82. The study involved 2,804 men and 3,000 women (total 5804) with a history of, or risk factors for, vascular disease. They were assigned into groups of either a statin (pravastatin) or placebo and the study lasted for just over 3 years. Total deaths and adverse events of heart attack, stroke, cancer etc were measured.

The results of the study revealed:
(a) Total serious adverse events were the same in both groups.
(b) Heart disease was 19% higher in the placebo group.
(c) Stroke risk was 3% higher in the pravastatin group.
(c) Cancer risk was 25% higher in the pravastatin group.
(d) Total death rates were 6% higher in the pravastatin group.

The results show that 3 years of statin treatment did not add one day to the life of the participants of the trial.

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Statins increase the risk of colon adenomas by 54%

This study was published in the Journal of gastrointestinal cancer 2011 Sep 6

Study title and authors:

Association of Type 2 Diabetes and Colon Adenomas.

Eddi R, Karki A, Shah A, Debari VA, Depasquale JR.

Division of Gastroenterology, Seton Hall University School of Health and Medical Sciences, South Orange, NJ, USA, rodney_eddi@yahoo.com.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21894459

An adenoma is a benign tumor (-oma) of glandular origin. Adenomas can grow from many organs including the colon, adrenal glands, pituitary gland, thyroid, prostate, etc. Although these growths are benign, over time they may progress to become malignant, at which point they are called adenocarcinomas. Even while benign, they have the potential to cause serious health complications by compressing other structures (mass effect) and by producing large amounts of hormones in an unregulated, non-feedback-dependent manner (paraneoplastic syndrome).

The thiazolidinediones also known as glitazones, are a class of medications used in the treatment of type 2 diabetes.

This study, which lasted 3 years, of 783 people (of which 261 had adenomas) sought to determine (i) the association between type 2 diabetes and colon adenomas and (ii) factors that increase the risk of adenomas.

The study found;
(i) Those who had diabetes had a 45% increased risk of developing colon adenomas.
(ii) Factors that increased the risk of adenomas included:
(a) Exposure to insulin increased the risk of adenoma by 73%.
(b) Exposure to thiazolidinediones increased the risk of adenoma by 183%.
(c) Exposure to smoking increased the risk of adenoma by 47%.
(d) Use of aspirin increased the risk of adenoma by 59%.
(e) Use of statins increased the risk of adenoma by 54%.

To conclude: This study shows a significant association between type 2 diabetes and colon adenomas. Colon adenomas are shown to be associated with smoking and various pharmaceutical drugs such as statins, aspirin and thiazolidinediones. Colon adenomas have the potential to cause serious health complications including progressing to become cancerous.

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Statin users have a 37% increase in gastric cancer risk

This paper was published in Hepatogastroenterology 2011 May-Jun;58(107-108):1057-61

Study title and author:

Statins and gastric cancer risk.

Shimoyama S

Gastrointestinal Unit, Settlement Clinic, Towa, Tokyo, Japan. shimoyama@apost.plala.or.jp

This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21830442

This paper reviewed the scientific literature concerning the effect of statins on gastric cancer incidence published between 1993 and 2008.

The author found:
(a) Statin users had a 37% increase in gastric cancer risk.
(b) Statin users had a 20% increase in upper gastrointestinal cancer.

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Statin users are at an increased risk for reccurence of prostate cancer following removal of the prostate

This post includes a  synopsis of a study published in British Journal of Urology international 2011 Mar 31 and a recipe for pad thai.

Study title and authors:
Effect of statin use on biochemical outcome following radical prostatectomy.

Books:

Ritch CR, Hruby G, Badani KK, Benson MC, McKiernan JM.

Columbia University Medical Center/NY Presbyterian Hospital, New York, USA.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21453350
 
The objective of the study was to determine the relationship between statin use and biochemical recurrence (cancer reccuring) following radical prostatectomy (removal of the prostate). 1261 patients were analysed of which 281 were statin users.

The study found:
(a) Statin users had a 54% increased risk of prostate cancer reccuring compared to non-statin users.
(b) Statin users had a lower 5-year survival compared with non-statin users.

To conclude: Statin users are at an increased risk for reccurence of prostate cancer following removal of the prostate.

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall 

Recipe of the day

Pad Thai

Ingredients:

Food Mall: Duck Breast

◦1 lb duck breast (chicken thighs, shrimp, sirloin would all work well)

◦1/4 c fat (butter, coconut oil, or bacon fat)
◦2 zucchinis
◦1 onion
◦4 cloves garlic
◦1 T apple cider vinegar
◦2 T fresh ginger, minced
◦3 T almond butter
◦1 T chili garlic sauce
◦1 T fish sauce (optional)
◦1 lime, juiced
◦sliced green onions
◦s&p

Method:
For the duck, melt the fat in a large saute pan over medium high heat. Salt and pepper the duck. Add to the pan and sear, skin side down, until you get a nice, crispy crust, about 8 minutes. Flip it over and sear on the other side, about another 7 minutes. Remove the duck from the pan, let it rest and drain the rendered fat from the pan, until you have about 1/2 cup in the pan–just a rough measure.

While the duck is going…

If you have a mandoline, get it out and start slicing the zuchinnis lengthwise. If you don’t have one, you can get one on the cheap at TJ Maxx or you can get it from Amazon (check out our ‘Must Haves’ on the right)…or you can use a knife to slice the zukes as thinly as you can (lengthwise). Then slice them into thin strips, just like a noodle. Another option, for speed, lack of the proper tools or sheer laziness, you can just chop the zukes into chunks. Not quite the same effect, but same flavor.

In the reserved fat, saute the onion, garlic and ginger, until soft. Add the fish sauce, chili sauce, vinegar, lime juice and almond butter. Stir to combine.

Add the zuke noodles to the saute pan. Stir them around to get the sauce incoporated onto the “zoodles”. The point here is get the “zoodles” hot and very slightly cooked through (just like an al dente noodle!), about 10 minutes.

Serve hot and topped with a squeeze of lime juice and some chopped green onions.

Pad Thai



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Statins increase the risk of prostate cancer

This post contains a synopsis of a study published in The Prostate 2011 Apr 7 and a recipe for bacon wrapped sweet potato fries with chipotle lime dip.

Study title and authors:
Statins increase the risk of prostate cancer: A population-based case-control study.
Chang CC, Ho SC, Chiu HF, Yang CY.
Department of Environmental and Occupational Health, National Cheng Kung University, Tainan, Taiwan.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21480313

Books:

The aim of the study was to investigate whether the use of statins was associated with prostate cancer risk. The study examined 388 prostate cancer cases and 1,552 controls.

The study results revealed:
(a) Those who used statins had a significant 55% increase in prostate cancer risk compared to those with no use of statins.
(b) Those who had the lowest statin dose had a 17% increase in prostate cancer risk compared to those with no use of statins.
(c) Those who had the highest statin dose had an 86% increase in prostate cancer risk compared to those with no use of statins.

To conclude: Statins increase the risk of prostate cancer and the higher the statin dose, the higher the risk of cancer.

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall

Recipe of the day

Bacon Wrapped Sweet Potato Fries with Chipotle Lime Dip


Ingredients:

Food Mall: Bacon

◦2 sweet potatoes, cut into thick matchsticks

◦1 package bacon, don’t use thick cut
◦1/2 c mayo, using avocado oil
◦1-2 chipotles in adobo sauce
◦1 lime, juiced

Method:
Get your oven to 425°F. Soak the sweet potato matchsticks in a bowl of cold water for up to 6 hours. This removes a lot of the starch from the potato. When you remove the potatoes, you can visibly see white starch granules at the bottom of the bowl. Drain the water from the potatoes and pat dry.

Slice each piece of bacon in half, lengthwise. Wrap 1 strip of bacon around 1 matchstick sweet potato. Lay on a baking sheet. Repeat until all the bacon is gone. If you have left over sweet potatoes, toss ‘em on the pan too, they’ll cook beautifully in all the rendered bacon fat.

For the Dip:
In a food processor, pulse up the chipotle(s) and lime juice into the mayo.

Bake the fries for about 25 minutes on one side. You’re looking for browned bacon. Use some tongs to flip the fries over and bake for another 10-12 minutes, until browned.

Squeeze some lime juice on the fries. Serve hot and with the dip.

Bacon Wrapped Fries



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Statins increase cancer rates by 41% and the overall death rate by 4%

This post includes a summary of a study published in the American Journal of Cardiology 2001 May 1;87(9):1074-9 and arecipe for bacon wrapped roast beef with mustard and horseradish.

Study title and authors:
Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatin.

Books:

Downs JR, Clearfield M, Tyroler HA, Whitney EJ, Kruyer W, Langendorfer A, Zagrebelsky V, Weis S, Shapiro DR, Beere PA, Gotto AM.

Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, Texas, USA.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11348605

This study examined the effects of 20 to 40 mg/day of lovastatin in 6,605 generally healthy middle-aged and older men and women. 3,304 people received the statin drug and 3,301 people received a placebo.

The study found that the statin drug reduced the risk of a first acute major coronary event by 37%. However the statin drug also increased cancer rates by 41% and increased the overall death rate by 4%.

More information on this subject: Books : Scientific Studies : Other Websites : Videos : Food Mall 

Recipe of the day

Bacon wrapped roast beef with mustard and horseradish

Serves 4

Ingredients:

Food Mall: Sirloin Roast Beef

•3 1/2 lb top sirloin roast beef;

•6 slices bacon;
•¼ cup softened butter, clarified butter or other cooking fat;
•3 cloves garlic, minced;
•1 tbsp of Dijon or homemade mustard;
•1 tbsp good quality or homemade horseradish;
•3/4 cup red wine;
•1 3/4 cups homemade beef stock;

Preparation:
1.Preheat your oven to 400 F.

2.In a small bowl, combine the butter or other cooking fat, garlic, mustard and horseradish. Mix until smooth.

3.Rub the roast all over with the mixture.

4.Lay the bacon pieces out flat so that they are slightly overlapping. Then place the roast on top of the bacon and wrap the pieces around the roast. If needed, use toothpicks to hold the bacon in place.

5.Place the roast in a roasting dish and cook at 400 F for 20 minutes.

6.Once the roast has been in for 20 minutes, add the wine and stock to the roasting dish. At the same time, adjust the heat to 350 F.

7.Roast for about 70 minutes, depending on how well-done you like your meat. 20 minutes per pound is a good rule of thumb for a medium rare to medium well roast. There is a good reference chart included in the cookbook to know the exact roasting times of the different cuts of meat.

Bacon Wrapped Roast Beef with Mustard and Horseradish



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