Friday, 2 November 2012

Statins increase the risk of adverse medical events by 39%

This study was published in Clinical Therapeutics 2006 Jan;28(1):26-35

Study title and authors:
Statin-related adverse events: a meta-analysis.
Silva MA, Swanson AC, Gandhi PJ, Tataronis GR.
Massachusetts College of Pharmacy and Health Sciences, Worcester, Massachusetts 01608, USA. msilva@wor.mcphs.edu

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16490577

This study is a meta-analysis of statin randomized clinical trials that compare the number of adverse effects caused by statin treatment or placebo. The search through medical databases found 18 trials including 71,108 persons, and 301,374 person-years of follow-up. There were 36,062 persons receiving a statin and 35,046 receiving a placebo. (An adverse event is any untoward medical occurrence in a patient administered a pharmaceutical product).

The study found that statin therapy increased the risk of adverse events by 39%.

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