Antiphospholipid antibodies (indicate an increased risk of blood clots or pregnancy loss) are associated with statin use

This study was published in the Journal of Clinical Pathology 2012 Jun;65(6):551-6

 

Study title and authors:

High antiphospholipid antibody levels are associated with statin use and may reflect chronic endothelial damage in non-autoimmune thrombosis: cross-sectional study.

Broder A, Tobin JN, Putterman C.

Division of Rheumatology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York, USA. abroder@montefiore.org

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22389514

Persistently elevated antiphospholipid antibodies and positive lupus anticoagulant are associated with an increased risk of thrombosis and pregnancy loss, see here and here.

The study explored whether antiphospholipid antibodies and positive lupus anticoagulant were associated with statin use in 270 patients without autoimmune diseases hospitalised with arterial or venous thrombosis (blood clots).

The study found that statin users were 220% more likely to have antiphospholipid antibody positivity.