This study was published in the Annals of the Rheumatic Diseases 2008 May;67(5):614-9 Study title and authors:Increased exposure to statins in patients developing chronic muscle diseases: a 2-year retrospective study.Sailler L, Pereira C, Bagheri A, Uro-Coste E, Roussel B, Adoue D, Fournie B, Laroche M, Zabraniecki L, Cintas P, Arlet P, Lapeyre-Mestre M, Montastruc JL.Unit of Pharmacoepidemiology, EA 3696, Clinical Pharmacology Department, Paul Sabatier University, 37 Allées Jules Guesdes, 31000 Toulouse, France. sailler.l@chu-toulouse.fr This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17768174This...
Monday, 28 January 2013
High-fibre supplement (psyllium) linked to colon cancer risk
This study was published in the Lancet 2000 Oct 14;356(9238):1300-6 Study title and authors:Calcium and fibre supplementation in prevention of colorectal adenoma recurrence: a randomised intervention trial. European Cancer Prevention Organisation Study Group.Bonithon-Kopp C, Kronborg O, Giacosa A, Räth U, Faivre J.Registre Bourguignon des Tumeurs Digestives, Faculté de Médecine de Dijon, France. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11073017Ispaghula husk is a soluble fibre that comes from a shrub-like herb, Plantago psyllium. Ispaghula husk is also known...
Sunday, 27 January 2013
Abdominal aortic aneurysms expand more with statin use
This study was published in the American Heart Journal 2010 Feb;159(2):307-13 Study title and authors:Association of statin prescription with small abdominal aortic aneurysm progression.Ferguson CD, Clancy P, Bourke B, Walker PJ, Dear A, Buckenham T, Norman P, Golledge J.Vascular Biology Unit, Department of Surgery, School of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20152231Abdominal aortic aneurysm is recognized as an important cause of death in older men. An abdominal aortic...
Saturday, 26 January 2013
Low cholesterol leads to an early death
This study was published in the ScientificWorld Journal 2012;2012:930139 Study title and authors:Lipids and all-cause mortality among older adults: a 12-year follow-up study.Cabrera MA, de Andrade SM, Dip RM.Postgraduate Program in Public Health, State University of Londrina-UEL, Robert Koch Avenue, 60 CEP, 86038440 Londrina, PR, Brazil. marcoscabrera@uol.com.brThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22666169This study investigated the association between cholesterol levels and death rates in elderly people. The study lasted for 12 years and included 800 people aged...
Thursday, 24 January 2013
Statins may induce interstitial lung disease
This paper was published in Chest 2008 Oct;134(4):824-30Study title and authors:Statins and interstitial lung disease: a systematic review of the literature and of food and drug administration adverse event reports.Fernández AB, Karas RH, Alsheikh-Ali AA, Thompson PD.Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18689579This study reviewed the scientific literature to examine the relationship between statins and interstitial lung disease. (Interstitial lung disease is the name for...
Wednesday, 23 January 2013
Walking is associated with lower total death rates and lower death rates from cardiovascular disease in adults with diabetes
This study was published in the Archives of Internal Medicine 2003 Jun 23;163(12):1440-7Study title and authors:Relationship of walking to mortality among US adults with diabetes.Gregg EW, Gerzoff RB, Caspersen CJ, Williamson DF, Narayan KM.Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA. edg7@cdc.govThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12824093The objective of the study was to estimate the association between walking and the risk of death...
Tuesday, 22 January 2013
Use of statins is associated with increased insulin resistance in patients undergoing coronary artery bypass grafting
This study was published in Diabetes Care 2012 Oct;35(10):2095-9Study title and authors:Statin intake is associated with decreased insulin sensitivity during cardiac surgery.Sato H, Carvalho G, Sato T, Hatzakorzian R, Lattermann R, Codere-Maruyama T, Matsukawa T, Schricker T.Department of Anaesthesia, Royal Victoria Hospital, McGill University Health Center, Montreal, Quebec, Canada. hsatou@yamanashi.ac.jpThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22829524 This study investigated the association between preoperative statin therapy and insulin sensitivity during...
Low cholesterol levels are associated with a higher risk of Alzheimer's
This study was published in the Archives of Neurology 2004 May;61(5):705-14Study title and authors:Relation of plasma lipids to Alzheimer disease and vascular dementia.Reitz C, Tang MX, Luchsinger J, Mayeux R.Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15148148This study investigated the relationship between cholesterol levels and Alzheimer disease and vascular dementia. (Vascular dementia is caused by problems in the supply of blood to the brain usually from...
Monday, 21 January 2013
Statins increase the risk of diabetes
This study was published in Circulation 2010; 122: A14293Study title and authors:Does Therapy With Statins Increase Risk Of Diabetes?Renata Giudice; Giovanni de Simone; Raffaele Izzo; Marina De Marco; Valentina Trimarco; Teresa Migliore; Gerardo Carpinella; Marcello Chinali; Nicola De Luca; Bruno TrimarcoFederico University, Naples, Italy ...
Sunday, 20 January 2013
High cholesterol levels associated with exceptional longevity in men
This study was published in the Archives of Internal Medicine 2008 Feb 11;168(3):284-90Study title and authors:Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years.Yates LB, Djoussé L, Kurth T, Buring JE, Gaziano JM.Division of Aging, Brigham and Women's Hospital, 1620 Tremont St, Boston, MA 02120, USA. lbyates@partners.orgThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18268169 The study examined factors associated with a life span of 90 or more in men. The study lasted 25 years and included 2,357 men. Regarding...
Friday, 18 January 2013
Rhabdomyolysis induced by statins
This paper was published in Clinical Chemistry 1990 Dec;36(12):2145-7Study title and authors:Rhabdomyolysis secondary to lovastatin therapy.Manoukian AA, Bhagavan NV, Hayashi T, Nestor TA, Rios C, Scottolini AG.Department of Pathology, John A. Burns School of Medicine, University of Hawaii, Honolulu 96822.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2253372This paper reports a case of lovastatin (Mevacor)-induced rhabdomyolysis (severe muscle breakdown which may lead to kidney damage).(i) A 59 year old woman was admitted to hospital with a two day history of shortness of breath...
Walking increases longevity in the elderly
This study was published in Maturitas 2012 Dec 29. pii: S0378-5122(12)00400-8 Study title and authors:Walking four times weekly for at least 15min is associated with longevity in a Cohort of very elderly people.Fortes C, Mastroeni S, Sperati A, Pacifici R, Zuccaro P, Francesco F, Agabiti N, Piras G, Amleto D, Ebrahim S.Clinical Epidemiology Unit, IDI-IRCSS, Rome, Italy. Electronic address: c.fortes@idi.it. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23280132This study investigated the role of walking outdoors on longevity. The study lasted for ten years and included...
Wednesday, 16 January 2013
Autoimmune hepatitis can be triggered by statins
This paper was published in the Journal of Clinical Gastroenterology 2006 Sep;40(8):757-61 Study title and authors:Autoimmune hepatitis triggered by statins.Alla V, Abraham J, Siddiqui J, Raina D, Wu GY, Chalasani NP, Bonkovsky HL.Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16940892This paper describes three patients in whom it is probable that statins initiated the development of autoimmune hepatitis. (Autoimmune hepatitis is inflammation of the liver that occurs...
Tuesday, 15 January 2013
Red meat is a rich source of micronutrients
This study was published in the British Journal of Nutrition 2005 Jun;93(6):933-42 Study title and authors:Consumption of red meat, white meat and processed meat in Irish adults in relation to dietary quality.Cosgrove M, Flynn A, Kiely M.Department of Food and Nutritional Sciences, University College Cork, Republic of Ireland. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16022764The aim of the study was to examine the association of red meat, white meat and processed meat consumption in Irish adults with dietary quality. The study reviewed the diets of 662 men...
Monday, 14 January 2013
Lovastatin (Mevacor) may be associated with the onset of lupus
This study was published in the Archives of Internal Medicine 1991 Aug;151(8):1667-8 Study title and authors:Lovastatin-induced lupus erythematosus.Ahmad S.Cardio-Diagnostic Clinique, Fairmont, WVa 26554. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1872674This paper describes two patients; a 64-year-old woman and a 40-year-old man, who developed a lupuslike syndrome due to lovastatin therapy. (Lupus is an autoimmune disease where the body's immune system attacks its own cells and tissue, resulting in inflammation and tissue damage).The lovastatin-induced...
Low cholesterol is the most common risk factor for brain hemorrhage in people under 40
This study was published in Stroke 1999 Mar;30(3):537-41 Study title and authors:Intracerebral hemorrhage in young people: analysis of risk factors, location, causes, and prognosis.Ruíz-Sandoval JL, Cantú C, Barinagarrementeria F.Stroke Clinic, Stroke Program, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10066848This study investigated the risk factors for intracerebral (brain) hemorrhage in young people. The study included 200 patients, aged 15 to 40 years, with confirmed intracerebral hemorrhage.The...
Saturday, 12 January 2013
Guillain-Barre syndrome may be a serious side-effect of statin treatment
This paper was published in Muscle and Nerve 2004 Nov;30(5):663-6Study title and authors:Disorder resembling Guillain-Barré syndrome on initiation of statin therapy.Rajabally YA, Varakantam V, Abbott RJ.Department of Neurology, University Hospitals of Leicester, Royal Infirmary, Leicester LE1 5WW, United Kingdom. yusuf.rajabally@uhl-tr.nhs.uk This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15389662This paper reports the case of a 58-year-old man with Guillain-Barre syndrome. Guillain-Barre syndrome is a serious condition of the peripheral nervous system. It occurs when the body's...
Friday, 11 January 2013
Red meat decreases the risk of heart disease
This study was published in Preventive Medicine 2007 Feb;44(2):135-42 Study title and authors:Health-related behaviours as predictors of mortality and morbidity in Australian Aborigines.Burke V, Zhao Y, Lee AH, Hunter E, Spargo RM, Gracey M, Smith RM, Beilin LJ, Puddey IB.University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital Unit, Box X2213 GPO, Perth 6847, Australia. vburke@cyllene.uwa.edu.au This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17069878?dopt=AbstractThe study examined the influence of diet and lifestyle on the risk of...
Thursday, 10 January 2013
Statins may be associated with amyotrophic lateral sclerosis
This study was published in Drug Safety 2009;32(8):649-61Study title and authors:Amyotrophic lateral sclerosis-like conditions in possible association with cholesterol-lowering drugs: an analysis of patient reports to the University of California, San Diego (UCSD) Statin Effects Study.Golomb BA, Kwon EK, Koperski S, Evans MA.Department of Medicine, University of California, San Diego, California 92093-0995, USA. bgolomb@ucsd.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19591530Dr Golomb notes that cases of amyotrophic lateral sclerosis (ALS) or ALS-like conditions have...
Wednesday, 9 January 2013
Consumption of sugar-sweetened and low-calorie sodas are associated with a significantly higher risk of stroke
This study was published in the American Journal of Clinical Nutrition 2012 May;95(5):1190-9Study title and authors:Soda consumption and the risk of stroke in men and women.Bernstein AM, de Koning L, Flint AJ, Rexrode KM, Willett WC.Wellness Institute of Cleveland Clinic, Lyndhurst, OH 44124, USA. bernsta2@ccf.orgThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22492378The study examined the relationship between soda consumption and the risk of stroke. Data was extracted from two studies:(i) The Nurses' Health Study, a study of 84,085 women followed for 28 years.(ii) The...
Antiphospholipid antibodies (indicate an increased risk of blood clots or pregnancy loss) are associated with statin use
This study was published in the Journal of Clinical Pathology 2012 Jun;65(6):551-6 Study title and authors:High antiphospholipid antibody levels are associated with statin use and may reflect chronic endothelial damage in non-autoimmune thrombosis: cross-sectional study.Broder A, Tobin JN, Putterman C.Division of Rheumatology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York, USA. abroder@montefiore.org This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22389514Persistently elevated antiphospholipid antibodies and positive lupus anticoagulant...
Monday, 7 January 2013
High red meat consumption is associated with a reduced risk of cancer
This study was published in the British Medical Journal 1997 Oct 18;315(7114):1018 Study title and authors:Frequent consumption of red meat is not risk factor for cancer.Cox BD, Whichelow MJ. This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9365318This study investigated the association between diet and the risk of cancer. The study lasted for seven years and included 1,630 men and 2,030 women who were free of cancer at the start of the study.Regarding red meat consumption, the study found:(a) Men who consumed red meat everyday had an ~18% reduced risk of cancer...
Sunday, 6 January 2013
Rosuvastatin (Crestor) is associated with a 2.8-fold increased risk of lung cancer
This study was published in the Libyan Journal of Medicine 2012 Dec 27;7(0):1-3 Study title and authors:Statins use and female lung cancer risk in Taiwan.Lai SW, Liao KF, Lin CL, Sung FC, Cheng YH.School of Medicine, China Medical University, Taichung, Taiwan; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23272648This study investigated the assoiation between statins and lung cancer in women. The study included 1,117 women with newly diagnosed lung cancer, average...
Low-fat, low-cholesterol diets increase the risk of heart disease
This study was published in the Journal of Clinical Investigation 1990 Jan;85(1):144-51 Study title and authors:A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates.Brinton EA, Eisenberg S, Breslow JL.Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York, New York 10021. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2104877Scientific evidence suggests that high levels of high density lipoprotein (HDL) cholesterol and apolipoproteins A-I may offer protection from...
Saturday, 5 January 2013
Statin use associated with increased risk of brain hemorrhage after stroke treatment
This study was published in Stroke 2009 May;40(5):1729-37 Study title and authors:Prior statin use, intracranial hemorrhage, and outcome after intra-arterial thrombolysis for acute ischemic stroke.Meier N, Nedeltchev K, Brekenfeld C, Galimanis A, Fischer U, Findling O, Remonda L, Schroth G, Mattle HP, Arnold M.Department of Neurology, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19265056Ischemic stroke occurs when an artery to the brain is blocked. Intra-arterial thrombolysis is a medical...
Thursday, 3 January 2013
Professor says that long-term consumption of plant sterol-enriched margarines may increase cardiovascular risk
This study was published in the British Medical Journal Case Reports 2009;2009. pii: bcr10.2008.1108Study title and authors:Extravascular lipid deposit (xanthelasma) induced by a plant sterol-enriched margarine.Vergès B, Athias A, Petit JM, Brindisi MC.Hôpital du Bocage, 2 Bd Maréchal de Lattre de Tassigny, Dijon 21000, France.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21822448A 59 year old woman consumed a plant sterol-enriched margarine of 20 g/day (Fruit d’Or Pro-activ margarine, containing 8% phytosterols), corresponding to 1.6 g/day phytosterols. (i) After 18 months...
Wednesday, 2 January 2013
Statins increase the risk of muscle adverse reactions
This study was published in Muscle and Nerve 2011 Dec;44(6):877-81Study title and authors:Prevalence and risk factors of muscle complications secondary to statins.El-Salem K, Ababneh B, Rudnicki S, Malkawi A, Alrefai A, Khader Y, Saadeh R, Saydam M.Department of Neurosciences, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan. khalidelsalem@hotmail.comThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22102457The aim of the study was to investigate the prevalence of muscle complications among patients using statins. The study included 345 patients...
The importance of cholesterol to healthy cell functioning
This study was published in Nature Communications 2012 Dec 4;3:1249Study title and authors:Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins.Sheng R, Chen Y, Yung Gee H, Stec E, Melowic HR, Blatner NR, Tun MP, Kim Y, Källberg M, Fujiwara TK, Hye Hong J, Pyo Kim K, Lu H, Kusumi A, Goo Lee M, Cho W.Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23212378Wonhwa Cho, professor of chemistry at the University of...
Tuesday, 1 January 2013
Doctor says that simvastatin should be considered among the causes of peripheral neuropathy
This study was published in the Journal of Neurology, Neurosurgery and Psychiatry 1995 May;58(5):625-8Study title and authors:Peripheral neuropathy associated with simvastatin.Phan T, McLeod JG, Pollard JD, Peiris O, Rohan A, Halpern JP.Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Australia.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7745415This paper describes four patients who developed sensorimotor neuropathy (sensorimotor neuropathy is a type of peripheral neuropathy that damages the motor nerves and the sensory nerves) while...
Subscribe to:
Posts (Atom)
