Monday, 6 February 2012

High carbohydrate diets increase the risk of diabetes

This study was published in Metabolism 1996 Oct;45(10):1267-72

Study title and authors:
Lipoproteins, apolipoproteins, and low-density lipoprotein size among diabetics in the Framingham offspring study.
Siegel RD, Cupples A, Schaefer EJ, Wilson PW.
Division of Endocrinology, Diabetes, Metabolism, and Molecular Medicine, New England Medical Center, Boston, MA 02111, USA.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8843183

This study compared values for triglycerides, very low density lipoprotein (VLDL) cholesterol, low density lipoprotein (LDL) cholesterol particle size, apolipoprotein B (apoB), apolipoprotein A-1 (apo A-1) and high density lipoprotein (HDL) cholesterol were analyzed in 174 diabetic and 3,757 nondiabetic subjects and data from a total of 2,025 men and 2,042 women were subjected to statistical analysis.

The study found:
  • Diabetics have higher triglyceride levels than non diabetics.
  • Diabetics have higher VLDL cholesterol levels than non diabetics.
  • Diabetics have more small dense LDL cholesterol particles than non diabetics.
  • Diabetes is not associated with elevated LDL cholesterol levels.
  • Diabetics have more apolipoprotein B than non diabetics.
  • Diabetics have less apolipoprotein A-1 than non diabetics.
  • Diabetics have less HDL cholesterol than non diabetics.
All the above markers for diabetes are caused by a diet high in carbohydrate and low in fat see here.

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