Monday, 19 December 2011

Low cholesterol levels are associated with an increase in death rates especially from cancer

This study was published in the British Medical Journal 1995 Aug 12;311(7002):409-13

Study title and authors:
Low serum total cholesterol concentrations and mortality in middle aged British men.
Wannamethee G, Shaper AG, Whincup PH, Walker M.
Department of Public Health, Royal Free Hospital School of Medicine, London.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7640584

7,735 men aged 40-59 were followed for nearly 15 years to examine the relationship between low cholesterol levels and causes of mortality.

The study found:
(a) Men with low cholesterol (below 4.8 mmol/l (185 mg/dL)) had a 60% increase in total death rates compared to men with cholesterol between 4.8-5.9 mmol/l (185-228 mg/dL).
(b) Men with low cholesterol (below 4.8 mmol/l (185 mg/dL)) had a significant increase in cancer death rates compared to men with cholesterol between 4.8-5.9 mmol/l (185-228 mg/dL).
(c) Low cholesterol levels were associated with an increased prevalence of several diseases and indicators of ill health.

To conclude: Low cholesterol levels are associated with an increase in death rates especially from cancer.

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