This study was published in the Annals of Surgery 2009 Sep;250(3):395-402 Study title and authors:Parenteral fish oil improves outcomes in patients with parenteral nutrition-associated liver injury.Puder M, Valim C, Meisel JA, Le HD, de Meijer VE, Robinson EM, Zhou J, Duggan C, Gura KM.Department of Surgery, Children's Hospital Boston and Harvard Medical School, Boston, MA, USA. mark.puder@childrens.harvard.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19661785?dopt=AbstractPlusThis study compared the safety and efficacy between a fish oil-based intravenous lipid emulsion...
Monday, 31 December 2012
Sunday, 30 December 2012
Analysis of 119 statin randomized controlled trials find that statins increase the risk of muscle problems
This study was published in Pharmacoepidemiology and Drug Safety 2007 Feb;16(2):132-43 Study title and authors:Systematic review and meta-analysis of clinically relevant adverse events from HMG CoA reductase inhibitor trials worldwide from 1982 to present.McClure DL, Valuck RJ, Glanz M, Hokanson JE.Kaiser Foundation Health Plan of Colorado, Clinical Research Unit, Denver, CO 80237-8066, USA. david.l.mcclure@kp.org This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17072896The objective of the study was to determine the association of adverse events from a systematic...
Friday, 28 December 2012
Consumption of sugar-sweetened drinks is associated with obesity in children
This study was published in the Lancet 2001 Feb 17;357(9255):505-8Study title and authors:Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis.Ludwig DS, Peterson KE, Gortmaker SL.Department of Medicine, Children's Hospital, Boston, MA 02115, USA. david.ludwig@tch.harvard.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11229668?dopt=AbstractPlusThe study examined the relationship between the consumption of sugar-sweetened drinks and obesity. The study included 548 schoolchildren (average age 11.7 years) who...
Wednesday, 26 December 2012
Pesticides associated to genetically modified foods found in pregnant women and their fetuses
This study was published in Reproductive Toxicology 2011 May;31(4):528-33 Study title and authors:Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada.Aris A, Leblanc S.Department of Obstetrics and Gynecology, University of Sherbrooke Hospital Centre, Sherbrooke, Quebec, Canada. aziz.aris@usherbrooke.ca This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21338670This study evaluated the blood levels of pesticides associated to genetically modified foods in pregnant and nonpregnant women. The...
Sunday, 23 December 2012
Statins are associated with an approximate doubling of the risk of muscle disease
This study was published in Clinical Therapeutics 2007 Aug;29(8):1761-70Study title and authors:Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 diabetic and nondiabetic patients.Nichols GA, Koro CE.Kaiser Permanente, Center for Health Research, Portland, Oregon 97227-1098, USA. greg.nichols@kpchr.orgThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17919557The objective of this study was to determine the prevalence of myopathy (muscle disease) among subjects with or without diabetes, some of whom received statin treatment. the...
High-fat diets reduce the risk of mild cognitive impairment or dementia
This study was published in the Journal of Alzheimers Disease 2012;32(2):329-39 Study title and authors:Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia.Roberts RO, Roberts LA, Geda YE, Cha RH, Pankratz VS, O'Connor HM, Knopman DS, Petersen RC.Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. roberts.rosebud@mayo.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22810099The objective of the study was to investigate the association between fat, protein & carbohydrate intake and mild cognitive...
Saturday, 22 December 2012
Suicide attempters have low cholesterol levels
This study was published in the Journal of Affective Disorders 2012 Dec 10. pii: S0165-0327(12)00799-9 Study title and authors:Plasma total cholesterol in psychiatric patients after a suicide attempt and in follow-up.Papadopoulou A, Markianos M, Christodoulou C, Lykouras L.Department of Psychiatry, Attikon General Hospital, Athens University Medical School, Greece. Electronic address: athanpapad@hotmail.gr. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23237826This study investigated the association of cholesterol levels with suicide attempts. The study included...
Thursday, 20 December 2012
Review of the scientific literature finds consistent evidence of an association between sugar intake and cardiovascular disease
This paper was published in the Internal Medicine Journal 2012 Oct;42 Suppl 5:46-58 Study title and authors:Sugar restriction: the evidence for a drug-free intervention to reduce cardiovascular disease risk.Thornley S, Tayler R, Sikaris K.Section of Epidemiology and Biostatistics, University of Auckland, Auckland, New Zealand. s.thornley@auckland.ac.nz This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23035683This paper reviewed the epidemiological, biochemical and psychological evidence that implicates excess sugar intake as an important cause of ill-health.The paper...
Wednesday, 19 December 2012
Statins increase the risk of muscle pain by 90%
This study was published in Circulation 2012 Nov 26 Study title and authors:The Effect of Statins on Skeletal Muscle Function.Parker BA, Capizzi JA, Grimaldi AS, Clarkson PM, Cole SM, Keadle J, Chipkin S, Pescatello LS, Simpson K, White CM, Thompson PD.1 Hartford Hospital, Hartford, CT; This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23183941This study assessed the effects of statins on muscle function. The study included 420 healthy subjects, who had never previously taken statins, who received either 80 mg of atorvastatin or placebo for six months.The study...
Meat may help to lower the incidence of demineralization and white spots on teeth
This study was published in Minerva Stomatologica 2010 Nov-Dec;59(11-12):583-91 Study title and authors:Oral implications of the vegan diet: observational study.Laffranchi L, Zotti F, Bonetti S, Dalessandri D, Fontana P.Doctoral school in "Medicine and Experimental Therapy", Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy. auralaff@libero.it This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21217622The aim of this study was to investigate oral changes in subjects who have assumed a vegan diet (a diet completely lacking in meat and...
Monday, 17 December 2012
Low fat diets associated with amenorrhoea
This study was published in Clinical Endocrinology 1999 Feb;50(2):229-35 Study title and authors:Functional hypothalamic amenorrhoea: a partial and reversible gonadotrophin deficiency of nutritional origin.Couzinet B, Young J, Brailly S, Le Bouc Y, Chanson P, Schaison G.Service d'Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, France. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10396367This study examined factors that lead to functional hypothalamic amenorrhoea. The study included 12 women (aged 22-35 years) with functional hypothalamic amenorrhoea and...
Sunday, 16 December 2012
Low-fat, low-cholesterol diets lead to growth failure in children
This study was published in the American Journal of Diseases of Children 1989 May;143(5):537-42 Study title and authors:Growth failure. A complication of dietary treatment of hypercholesterolemia.Lifshitz F, Moses N.Department of Pediatrics, North Shore University Hospital, Manhasset, NY 11030. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2718985This study describes the effects of a low-fat, low-cholesterol diet on eight children as treatment for "high cholesterol".The study found that the low-fat, low-cholesterol diet caused growth failure:(i)...
Saturday, 15 December 2012
Statins increase the risk of peripheral neuropathy by 30%
This study was published in the Journal of Diabetes 2012 Nov 1Study title and authors:The association of statin use with peripheral neuropathy in the US population 40 years of age or older.Tierney EF, Thurman DJ, Beckles GL, Cadwell BL.Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23121724Peripheral nerves carry information to and from the brain. They also carry signals to and from the spinal cord to the rest of the body. Peripheral neuropathy means these nerves don't work...
Women with amenorrhea consume only half the amount of dietary fat compared to women with regular menstrual cycles
This study was published in the Journal of Clinical Endocrinology and Metabolism 1998 Jan;83(1):25-32 Study title and authors:Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea.Laughlin GA, Dominguez CE, Yen SS.Department of Reproductive Medicine, University of California-San Diego School of Medicine, La Jolla 92093-0633, USA. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9435412This study assessed the association of dietary intake with functional hypothalamic amenorrhea. (functional hypothalamic amenorrhea is...
Friday, 14 December 2012
Low cholesterol levels are associated with an inreased risk of Hodgkin's disease
This study was published in Cancer 1992 Feb 15;69(4):1042-6Study title and authors:The prognostic significance of total serum cholesterol in patients with Hodgkin's disease.Muller CP, Trilling B, Steinke B.Medizinische Universitätsklinik II, Tübingen, Germany.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1735071The study investigated the prognostic significance of cholesterol levels at the time of diagnosis in patients with Hodgkin's disease. The study included 179 subjects and age- and sex-matched controls.The study found:(a) Cholesterol levels were significantly...
Wednesday, 12 December 2012
Statins increase the risk of birth defects, miscarriage and premature birth
This study was published in the British Journal of Obstetrics and Gynaecology 2012 Nov 30 Study title and authors:Pregnancy outcome following maternal exposure to statins: a multicentre prospective study.Winterfeld U, Allignol A, Panchaud A, Rothuizen L, Merlob P, Cuppers-Maarschalkerweerd B, Vial T, Stephens S, Clementi M, De Santis M, Pistelli A, Berlin M, Eleftheriou G, Maňáková E, Buclin T.STIS and Division of Clinical Pharmacology, University Hospital, Lausanne, Switzerland. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23194157The objective of the study was...
Tuesday, 11 December 2012
Diets high in saturated fat lead to lower levels of Lp(a)
This study was published in the Journal of Lipid Research 1992 Oct;33(10):1493-501Study title and authors:Effect of dietary cis and trans fatty acids on serum lipoprotein[a] levels in humans.Mensink RP, Zock PL, Katan MB, Hornstra G.Department of Human Biology, Limburg University, Maastricht, The Netherlands.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1431574The lead author of the study, Professor Ronald Mensink, notes that a high level of lipoprotein[a] (Lp[a]) is a strong risk factor for coronary heart disease.This study set out to determine the influence of saturated...
Monday, 10 December 2012
Cholesterol lowering treatment increases the risk of death
This study was published in Circulation 1990 Dec;82(6):1916-24 Study title and authors:An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence.Holme I.Life Insurance Companies' Institute for Medical Statistics, Ullevaal Hospital, Oslo, Norway. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2242517The study investigated the relationship between cholesterol reduction and death rates by analysing the results of 19 randomized clinical cholesterol reduction intervention trials (by drugs...
Statins may adversely affect cognition in patients with dementia
This study was published in the American Journal of Geriatric Pharmacotherapy 2012 Aug 22Study title and authors:The Effect of HMG: CoA Reductase Inhibitors on Cognition in Patients With Alzheimer's Dementia: A Prospective Withdrawal and Rechallenge Pilot Study.Padala KP, Padala PR, McNeilly DP, Geske JA, Sullivan DH, Potter JF.Geriatric Research Education and Clinical Center, Central Arkansas Veterans Health Administration System, Little Rock, Arkansas; Reynolds Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22921881The...
Saturday, 8 December 2012
Review of my book "Cholesterol and Saturated Fat Prevent Heart Disease" by Ilona from the "Big Fat Blog"
Here's a review of my book Cholesterol and Saturated Fat Prevent Heart Disease by Ilona from the "Big Fat Blog".The article can be accessed at: http://ilonadesign.blogspot.com.es/2012/11/cholesterol-and-saturated-fat-prevent.htmlIlona's articleCholesterol and Saturated Fat Prevent Heart Disease - David Evans David Evans compiled a great reference book - Cholesterol and Saturated Fat Prevent Heart Disease -about the relationship of Saturated fat in the diet and heart disease, showing that there is no correlation between these two elements. The book contains 101 scientific...
Friday, 7 December 2012
Small particle size LDL cholesterol associated with diabetes - Low fat diets lead to small particle size LDL cholesterol
This study was published in Arteriosclerosis, Thrombosis, and Vascular Biology 1995 Nov;15(11):1805-11Study title and authors:Effect of diabetes on lipoprotein size.Singh AT, Rainwater DL, Haffner SM, VandeBerg JL, Shelledy WR, Moore PH Jr, Dyer TD.Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7583559The effects of diabetes on low density lipoprotein (LDL) cholesterol particle sizes were assessed using samples from 94 subjects with type 2 diabetes and a similar number...
Thursday, 6 December 2012
Low cholesterol levels may lead to permanent psychomotor, cognitive, motorsystem damage, hypoadrenalism and infertility in both males and females
This study was published in the Journal of Ayub Medical College Abbottabad 2010 Jul-Sep;22(3):225-7Study title and authors:Hypocholesterolemia secondary to atrovastatin therapy.Ali S, Khan SA, Iram S.Department of Medicine, NIMS Medical College and Teaching Hospital, Abbottabad, Pakistan. drshafqutali@hotmail.comThis paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22338462This paper describes the case of a 40 years old male who was started on Atorvastatin after his angioplasty (angioplasty is the technique of mechanically widening narrowed or obstructed arteries) following a...
Wednesday, 5 December 2012
Higher fat consumption is associated with lower rates of colon cancer
This study was published in the International Journal of Cancer 2010 Aug 15;127(4):942-51 Study title and authors:Dietary fatty acids, luminal modifiers, and risk of colorectal cancer.Kato I, Majumdar AP, Land SJ, Barnholtz-Sloan JS, Severson RK.Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19998336This study assessed the association between fat intake and colorectal cancer. The study included 1,163 subjects with colon cancer and 1,501 healthy control subjects.The...
Tuesday, 4 December 2012
Low intake of dietary fat is associated with higher rates of hypothalamic amenorrhea
This study was published in the Journal of the Society for Gynecologic Investigation 1994 Jan-Mar;1(1):84-8Study title and authors:Hypothalamic amenorrhea and hidden nutritional insults.Warren MP, Holderness CC, Lesobre V, Tzen R, Vossoughian F, Brooks-Gunn J.Department of Obstetrics and Gynecology, St. Luke's-Roosevelt Hospital, New York, New York, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9419753The study examined the association between nutritional intake and hypothalamic amenorrhea. The study included 18 amenorrheic women who were compared to...
Monday, 3 December 2012
Low levels of low density Lipoprotein (LDL) cholesterol are associated with higher death rates in patients with acute heart failure
This study was published in Congestive Heart Failure 2012 Oct 16 Study title and authors:Low-Density Lipoprotein Levels in Patients With Acute Heart Failure.Kahn MR, Kosmas CE, Wagman G, Serrao GW, Fallahi A, Grady KM, Vittorio TJ.Department of Internal Medicine, Mount Sinai Medical Center, New York, NY This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/23066917This study investigated the association of cholesterol levels with death rates in patients hospitalised with heart failure. The study included 2,428 patients who were followed for 2.9 years.The study found that...
Sunday, 2 December 2012
Low dietary fat intake associated with hypothalamic amenorrhea
This study was published in the Journal of Clinical Endocrinology and Metabolism 1998 Jul;83(7):2309-12 Study title and authors:Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake.Miller KK, Parulekar MS, Schoenfeld E, Anderson E, Hubbard J, Klibanski A, Grinspoon SK.Neuroendocrine Unit, Massachusetts General Hospital, Boston 02114, USA. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9661600This study investigated factors that may lead to hypothalamic amenorrhea (hypothalamic...
High cholesterol levels predict higher survival rates in patients with acute coronary syndromes
This study was published in Clinical Cardiology 2009 Sep;32(9):E22-8 Study title and authors:Hypercholesterolemia paradox in relation to mortality in acute coronary syndrome.Wang TY, Newby LK, Chen AY, Mulgund J, Roe MT, Sonel AF, Bhatt DL, DeLong ER, Ohman EM, Gibler WB, Peterson ED.Division of Cardiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA. wang0085@mc.duke.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19645040This study investigated the association of cholesterol levels with in-hospital death...
Saturday, 1 December 2012
Statins cause definite damage to the peripheral nerves
This study was published in Neuro Endocrinology Letters 2011;32(5):688-90Study title and authors:Treatment with statins and peripheral neuropathy: results of 36-months a prospective clinical and neurophysiological follow-up.Otruba P, Kanovsky P, Hlustik P.Department of Neurology, Palacky University Medical School, University Hospital, Olomouc, Czech Republic. pavel.otruba@fnol.czThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22167150 This study investigated the effects of statin treatment on lower-limb peripheral nerves. The study included 42 patients on statin therapy...
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