This study was published in BMC Geriatricts 2011 Feb 22;11:8Study title and authors:Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).Freeman DJ, Robertson M, Brown EA, Rumley A, Tobias ES, Frölich M, Slagboom PE, Jukema JW, de Craen AJ, Sattar N, Ford I, Gaw A, Greer IA, Lowe GD, Stott DJ.Centre of Population and Health Sciences, University of Glasgow, Glasgow, UK. Dilys.Freeman@glasgow.ac.ukThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21342490The study aimed to determine the effect of pravastatin on venous...
Sunday, 30 September 2012
High saturated fat consumption is associated with a longer life in type one diabetics
This study was published in Diabetologia 2012 Aug;55(8):2132-41 Study title and authors:Dietary saturated fat and fibre and risk of cardiovascular disease and all-cause mortality among type 1 diabetic patients: the EURODIAB Prospective Complications Study.Schoenaker DA, Toeller M, Chaturvedi N, Fuller JH, Soedamah-Muthu SSDivision of Human Nutrition, Wageningen University, P.O. Box 8129, 6700 EV, Wageningen, The Netherlands. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22526612The study investigated the relationship of diet in cardiovascular disease and total death...
Friday, 28 September 2012
Analysis of 72 trials shows that statins increase the risk of diabetes by 9%
This study was published in QJM 2012 Feb;105(2):145-57Study title and authors:Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.Alberton M, Wu P, Druyts E, Briel M, Mills EJ.Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21920996This paper sought to identify different risk effects of statin therapy. The paper analysed seventy-two trials involving 159,458 patients.The paper found:(a) Statin users had a 9% increased risk...
Thursday, 27 September 2012
Pork helps to significantly increase nonheme-iron absorption
This study was published in the American Journal of Clinical Nutrition 2003 Jan;77(1):173-9Study title and authors:Nonheme-iron absorption from a phytate-rich meal is increased by the addition of small amounts of pork meat.Baech SB, Hansen M, Bukhave K, Jensen M, Sørensen SS, Kristensen L, Purslow PP, Skibsted LH, Sandström B.Research Department of Human Nutrition, The Royal Veterinary and Agricultural University, LMC Center for Advanced Food Studies, Frederiksberg, Denmark.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12499338The study investigated the effect of small...
Wednesday, 26 September 2012
Statin use increases the risk of type two diabetes
This study was published in the British Medical Journal 2012 Sep 13;2(5)Study title and authors:Do statins interfere with lifestyle intervention in the prevention of diabetes in primary healthcare? One-year follow-up of the FIN-D2D project.Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Vanhala M, Puolijoki H, Moilanen L, Tuomilehto J, Keinänen-Kiukaanniemi S, Uusitupa M.Pirkanmaa Hospital District, Tampere, Finland.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22983785The objective of the study was to examine whether the use of statins is associated with the incidence...
Tuesday, 25 September 2012
High soy consumption significantly increases the risk of prostate cancer
This study was published in the British Journal of Cancer 2004 May 4;90(9):1792-5Study title and authors:Do preserved foods increase prostate cancer risk?Jian L, Zhang DH, Lee AH, Binns CW.School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15208621?dopt=AbstractThe study investigated the association between food and prostate cancer risk. The study included 130 patients with prostate cancer and 274 controls without cancer.The study found:(a) Those who consumed over...
Monday, 24 September 2012
Low consumption of animal protein, fat, saturated fat, cholesterol and red meat is associated with higher rates of heart disease
This study was published in the American Journal of Clinical Nutrition 1999 Aug;70(2):221-7 Study title and authors:Dietary protein and risk of ischemic heart disease in women.Hu FB, Stampfer MJ, Manson JE, Rimm E, Colditz GA, Speizer FE, Hennekens CH, Willett WC.Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA. frank.hu@channing.harvard.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10426698The study examined the association between dietary protein intake and incidence of heart disease. The study included 80,082...
Statins are associated with decreased myocardial function
This study was published in Clinical Cardiology 2009 Dec;32(12):684-9 Study title and authors:Statin therapy decreases myocardial function as evaluated via strain imaging.Rubinstein J, Aloka F, Abela GS.Cardiology Division, Department of Medicine, Michigan State University, East Lansing, MI 48824, USA. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20027659The myocardium is the heart's muscular wall. It contracts to pump blood out of the heart, then relaxes as the heart refills with returning blood. This vital function pumps blood to the cells and tissues...
Saturday, 22 September 2012
Wheat bran inhibits the absorption of nonheme dietary iron
This study was published in the American Journal of Clinical Nutrition 1981 Aug;34(8):1469-78 Study title and authors:The inhibitory effect of bran on iron absorption in man.Simpson KM, Morris ER, Cook JD. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/6267927The study investigated the effects of whole wheat bran on the absorption of nonheme dietary iron. The study included 60 volunteers ranging in age from 19 to 42 years who consumed light meals with or without 12 grams of whole wheat bran added.The study found:(a) When 12 grams of bran was added to a light...
Lactic acidosis may develop as a complication of simvastatin therapy
This paper was published in Clinical Pharmacology and Therapeutics 2002 Oct;72(4):461-4Study title and authors:Simvastatin-induced lactic acidosis: a rare adverse reaction?Goli AK, Goli SA, Byrd RP Jr, Roy TM.Veterans Affairs Medical Center, Mountain Home, Tenn 37684-4000, USA.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12386648This paper describes a 53-year-old man with lactic acidosis. He had nausea, poor appetite, and progressive generalized weakness and malaise of 3 to 4 weeks’ duration. He had been taking simvastatin, 40 mg, every day for 3 years. Lactic...
Thursday, 20 September 2012
Zinc bioavailability from beef is about fourfold greater than from a high-fiber breakfast cereal.
This study was published in the American Journal of Clinical Nutrition 1993 Dec;58(6):902-7 Study title and authors:Measurement of zinc bioavailability from beef and a ready-to-eat high-fiber breakfast cereal in humans: application of a whole-gut lavage technique.Zheng JJ, Mason JB, Rosenberg IH, Wood RJ.Mineral Bioavailability Laboratory, US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8249876This study compared the effects of beef and breakfast cereals on...
Wednesday, 19 September 2012
Atorvastatin-induced acute pancreatitis
This study was published in the Journal of Pharmacology and Pharmacotherapeutics 2011 Jan;2(1):40-2Study title and authors:Atorvastatin-induced acute pancreatitis.Deshpande PR, Khera K, Thunga G, Hande M, Gouda ST, Nagappa AN.Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21701646This paper reports the case of a statin-induced acute pancreatitis.A 53-year-old patient developed acute pancreatitis after treatment with atorvastatin.After withdrawl of statin...
Soy has a pronounced inhibitory effect on the absorption of iron
This study was published in the American Journal of Clinical Nutrition 1981 Dec;34(12):2622-9Study title and authors:The inhibitory effect of soy products on nonheme iron absorption in man.Cook JD, Morck TA, Lynch SR.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7198374Three separate studies were performed in 36 men ranging in age from 18 to 50 years to determine the effects of various proteins on iron absorption.The studies comprised of:(i) Study I compared the effects of different proteins (egg protein, milk protein and isolated soy protein) on iron absorption....
Monday, 17 September 2012
Diets high in meat keep the bones healthy
This study was published in the Journal of Nutrition 2003 Apr;133(4):1020-6Study title and authors:Controlled high meat diets do not affect calcium retention or indices of bone status in healthy postmenopausal women.Roughead ZK, Johnson LK, Lykken GI, Hunt JR.Grand Forks Human Nutrition Research Center, Agricultural Research Service, U.S. Department of Agriculture, Grand Forks, ND 58202-9034, USA. froughea@gfhnrc.ars.usda.govThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12672913The study compared the effects of high and low meat diets on body calcium retention. The study...
Sunday, 16 September 2012
Statins are a potential cause of cholestatic hepatitis
This paper was published in the American Journal of Gastroenterology 1999 May;94(5):1388-90Study title and authors:Acute cholestatic hepatitis associated with pravastatin.Hartleb M, Rymarczyk G, Januszewski K.Department of Gastroenterology, Silesian Medical School, Katowice, Poland.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10235223This paper describes a 57 year old man with acute cholestatic hepatitis. (Acute cholestatic hepatitis is where the bile ducts of the liver become obstructed by inflammation and may lead to jaundice).The report found:The man's symptoms...
Saturday, 15 September 2012
Soy consumption inhibits the bioavailability of iron
This study can be accessed at the American Journal of Clinical Nutrition 1992 Sep;56(3):573-8Study title and authors:Soy protein, phytate, and iron absorption in humans.Hurrell RF, Juillerat MA, Reddy MB, Lynch SR, Dassenko SA, Cook JD.Nestec Ltd., Nestlé Research Centre, Lausanne, Switzerland.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1503071Soy protein isolate can be found in protein bars, meal replacement shakes, bottled fruit drinks, soups and sauces, meat analogs, baked goods, breakfast cereals and some dietary supplements.Soy is high in a substance called called...
Friday, 14 September 2012
Low levels of vitamin B12 linked to brain lesions
This study was published in the Journal of Neurology, Neurosurgery and Psychiatry 2009 Feb;80(2):149-57Study title and authors:Plasma vitamin B12 status and cerebral white-matter lesions.de Lau LM, Smith AD, Refsum H, Johnston C, Breteler MM.Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18977824White matter lesions are small areas of dead cells found in parts of the brain that act as connectors. They also appear in some cases of migraine headaches and in the brains of...
In postmenopausal women, a greater saturated fat intake is associated with less heart disease, whereas a low saturated fat intake is associated with the biggest increase in blocked arteries
This post includes a summary of a paper published in the American Journal of Clinical Nutrition, Vol. 80, No. 5, 1175-1184, November 2004Study title and authors:Dietary fats, carbohydrate, and progression of coronary atherosclerosis in postmenopausal women Dariush Mozaffarian, Eric B Rimm and David M Herrington From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, and the Departments of Epidemiology and Nutrition, Harvard School of Public Health, Boston (DM and EBR)This paper can be accessed at: http://www.ajcn.org/cgi/content/abstract/80/5/1175?ijkey=e4610ec5427b8118b39ec347e078d34a367efd11&keytype2=tf_ipsecshaThe...
Sunday, 9 September 2012
High levels of saturated fat and cholesterol consumption are associated with a reduced risk of multiple sclerosis
This study was published in the American Journal of Epidemiology 2000 Dec 1;152(11):1056-64 Study title and authors:Dietary fat in relation to risk of multiple sclerosis among two large cohorts of women.Zhang SM, Willett WC, Hernán MA, Olek MJ, Ascherio A.Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA. Shumin.Zhang@channing.harvard.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11117615This study investigated the relationship between fat and cholesterol consumption and the risk of multiple sclerosis. The study included 187,811...
Saturday, 8 September 2012
Acute hepatitis induced by lovastatin
This study was published in Digestive Diseases and Sciences 1994 Sep;39(9):2032-3Study title and authors:Acute hepatitis induced by HMG-CoA reductase inhibitor, lovastatin.Grimbert S, Pessayre D, Degott C, Benhamou JP.Service d'Hépatologie, Unité de Recherches de Physiopathologie Hépatique (INSERM U 24), Hôpital Beaujon, Clichy, France.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8082513This paper reports the case of an adult who suffered from clinical hepatitis three months after the onset of lovastatin administration.The patient suffered:(i) Loss of strength and energy.(ii)...
Friday, 7 September 2012
Statins double the risk of lupus
This study was published in Seminars in Arthritis Rheumatism 2011 Dec;41(3):373-81Study title and authors:Association between statin use and lupus-like syndrome using spontaneous reports.de Jong HJ, Tervaert JW, Saldi SR, Vandebriel RJ, Souverein PC, Meyboom RH, van Loveren H, Klungel OH.Laboratory for Health Protection Research, National Institute for Public Health and Environment, Bilthoven, Netherlands.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21868063The study assessed whether there was an association between statin use and the occurrence of lupus-like syndrome....
Thursday, 6 September 2012
Low cholesterol associated with hepatitis C related liver cancer
This study was published in the International Hepato Pancreato Biliary Association Journal 2010 Nov;12(9):625-36 Study title and authors:Evidence of aberrant lipid metabolism in hepatitis C and hepatocellular carcinoma.Wu JM, Skill NJ, Maluccio MA.Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. jw17@iupui.edu This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20961371The association of cholesterol levels with the hepatitis C virus (HCV) and HCV-related hepatocellular carcinoma (liver cancer) was assessed in 73 patients with...
Wednesday, 5 September 2012
Statins are associated with erectile dysfunction
This study was published in the Journal of Sexual Medicine 2010 Apr;7(4 Pt 1):1547-56Study title and authors:The effect of statin therapy on testosterone levels in subjects consulting for erectile dysfunction.Corona G, Boddi V, Balercia G, Rastrelli G, De Vita G, Sforza A, Forti G, Mannucci E, Maggi M.Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence Italy.This post can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20141585The aim of the study was to evaluate the association between statin therapy and erectile dysfunction. The study included 3,484...
Tuesday, 4 September 2012
Statins increase the risk of lupus by 67%
This study was published in Lupus 2012 Jul;21(8):885-9 Study title and authors:Statin-induced lupus: a case/non-case study in a nationwide pharmacovigilance database.Moulis G, Béné J, Sommet A, Sailler L, Lapeyre-Mestre M, Montastruc JL; French Association of PharmacoVigilance Centres.CHU Toulouse, Service de Médecine Interne, Toulouse, F-31059, France. guillaume.moulis@univ-tlse3.fr This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22333565The study examined the relationship between statins and lupus. Data from 235,147 adverse drug reports were analysed...
Monday, 3 September 2012
Low cholesterol associated with depression in elderly men
This study was published in the Lancet 1993 Jan 9;341(8837):75-9Study title and authors:Plasma cholesterol and depressive symptoms in older men.Morgan RE, Palinkas LA, Barrett-Connor EL, Wingard DL.Department of Community and Family Medicine, School of Medicine, University of California, San Diego, La Jolla 92093-0628.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8093404The study investigated the relationship between depressive illness and low cholesterol levels in 1,020 elderly men.The study found that among men aged 70 years and older, depression was three...
Sunday, 2 September 2012
Statins reduce libido
This paper was published in the British Journal of Clinical Pharmacology 2004 Sep;58(3):326-8 Study title and authors:Is decreased libido associated with the use of HMG-CoA-reductase inhibitors?de Graaf L, Brouwers AH, Diemont WL.Netherlands Pharmacovigilance Centre Lareb, Goudsbloemvallei 7, 5237 MH 's-Hertogenbosch, The Netherlands. l.degraaf@lareb.nl This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15327593The aim of the paper was to describe patients with decreased libido during use of statins, and to propose a hypothesis for this association....
Saturday, 1 September 2012
Saturated fat consumption is associated with a reduced risk of stroke
This study was published in the Journal of the American Medical Association 1997 Dec 24-31;278(24):2145-50Study title and authors:Inverse association of dietary fat with development of ischemic stroke in men.Gillman MW, Cupples LA, Millen BE, Ellison RC, Wolf PA.Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9417007 The objective of the study was to examine the association of stroke incidence with the intake of fat and type of fat among middle-aged...
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