This study was published in the European Journal of Clinical Nutrition 2012 Jun 20Study title and authors:Serum fatty-acid composition and the risk of Alzheimer's disease: a longitudinal population-based study.Rönnemaa E, Zethelius B, Vessby B, Lannfelt L, Byberg L, Kilander L.Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala Science Park, Uppsala, Sweden.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22713770The objective of the study was to ascertain whether saturated fat levels were associated with the risk of Alzheimer's disease....
Saturday, 30 June 2012
Friday, 29 June 2012
NSAIDs and statins increase the risk of renal cell carcinoma
This study was presented at the American Urological Association Annual Meeting; May 19-23, 2012; Atlanta, GA. Abstract 575.Study title and authors:NSAID and statin use and risk of renal cell carcinoma.Chéry L, Wright J, Hotaling J,This study can be accessed at: http://www.onclive.com/publications/urologists-in-cancer-care/2012/June-2012/NSAIDs-and-Statins-Have-No-Impact-on-Renal-Cell-Carcinoma-RiskNonsteroidal anti-inflammatory drugs, or NSAIDs are the most prescribed medications for treating conditions such as arthritis. Examples of NSAIDs are aspirin, ibuprofen, naproxen and...
Wednesday, 27 June 2012
Statins and erupting skin lesions
This paper was published in the Annales de Dermatologie et de Venereologie 2003 Feb;130(2 Pt 1):187-90Study title and authors:Simvastatin-induced lichen planus pemphigoidesStoebner PE, Michot C, Ligeron C, Durand L, Meynadier J, Meunier L.Service de Dermatologie-Allergologie-Photobiologie, Hôpital Saint-Eloi, 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5. p-stoebner@chu-montpellier.frThis paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12671581Lichen planus pemphigoides is a rare autoimmune blistering disease that is characterized by the development of erupting fluid...
Tuesday, 26 June 2012
Atorvastatin increases the death rate in diabetic patients
This study was published in Diabetes Care 2006 Jul;29(7):1478-85Study title and authors:Efficacy and safety of atorvastatin in the prevention of cardiovascular end points in subjects with type 2 diabetes: the Atorvastatin Study for Prevention of Coronary Heart Disease Endpoints in non-insulin-dependent diabetes mellitus (ASPEN).Knopp RH, d'Emden M, Smilde JG, Pocock SJ.Harborview Medical Center, 325 Ninth Ave., #359720, Seattle, WA 98104-2499, USA. rhknopp@u.washington.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16801565.1The purpose of the study was to assess the effect...
Monday, 25 June 2012
High cholesterol helps the elderly with high blood pressure to live a longer life
This study was published in the Journal of Hypertension 1990 Aug;8(8):755-61Study title and authors:Is a high serum cholesterol level associated with longer survival in elderly hypertensives?Staessen J, Amery A, Birkenhäger W, Bulpitt C, Clement D, de Leeuw P, Deruyttere M, De Schaepdryver A, Dollery C, Fagard R, et al.Klinisch Laboratorium Hypertensie, Inwendige Geneeskunde-Cardiologie, U.Z. Gasthuisberg, Leuven, Belgium.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2170516The study, which lasted over three years, investigated the relationship between cholesterol...
Sunday, 24 June 2012
Saturated fat and dietary cholesterol lower the risk of orofacial clefts
This study was published in the Journal of Nutrition 2004 Nov;134(11):3106-13Study title and authors:Maternal nutritional status and the risk for orofacial cleft offspring in humans.Krapels IP, van Rooij IA, Ocké MC, West CE, van der Horst CM, Steegers-Theunissen RP.Department of Epidemiology and Biostatistics, University Medical Center Nijmegen, Nijmegen, the Netherlands.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15514283The study investigated the effects of the mothers preconceptional diet on the risk of orofacial clefts in the offspring. Orofacial clefts are birth...
Pravastatin increases the risk of cancer by 6%
This paper was published in the Canadian Medical Association Journal 2007 Feb 27;176(5):649-54Study title and authors:Does pravastatin promote cancer in elderly patients? A meta-analysis.Bonovas S, Sitaras NM.Department of Pharmacology, School of Medicine, University of Athens Athens, Greece. sbonovas@med.uoa.grThis paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17325332The aim of the study was to assess the effect of pravastatin therapy on cancer risk. The study analysed the results of 12 pravastatin trials which included 42,902 men and women, (21,454 patients in pravastatin groups...
Friday, 22 June 2012
Low cholesterol levels increase the risk of death from stroke, cancer and all-causes
This study was published in the Journal of the American Medical Association 1995 Jun 28;273(24):1926-32Study title and authors:Serum total cholesterol and mortality. Confounding factors and risk modification in Japanese-American men.Iribarren C, Reed DM, Burchfiel CM, Dwyer JH.Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7783302The study investigated the relationship between cholesterol levels and death rates due to major causes. The study included 7,049 middle-aged...
Thursday, 21 June 2012
High consumption of animal fats decrease the risk of gout by 20%
This study was published in the American Journal of Clinical Nutrition 2003 Oct;78(4):690-701Study title and authors:A case-control study of the association of diet and obesity with gout in Taiwan.Lyu LC, Hsu CY, Yeh CY, Lee MS, Huang SH, Chen CL.Graduate Program of Nutrition, National Taiwan Normal University, Taipei, Taiwan. t10010@cc.ntnu.edu.twThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/14522726The purpose of this study was to explore potential dietary and lifestyle risk factors associated with gout in Chinese men. The study included 92 men with gout and 92 healthy...
Wednesday, 20 June 2012
Statin users have a 25% increased risk of developing Merkel cell carcinoma
This study was published in Cancer Epidemiology 2012 Jun 7Study title and authors:Increased incidence of Merkel cell carcinoma among younger statin users.Sahi H, Koljonen V, Böhling T, Neuvonen PJ, Vainio H, Lamminpää A, Kyyrönen P, Pukkala E.Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland; Department of Pathology, Helsinki University and HUSLAB, Helsinki, Finland.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22683172Merkel cell carcinoma is a rare type of skin cancer. It develops in Merkel cells which are in the top layer of the skin.The...
Tuesday, 19 June 2012
Saturated fat and dietary cholesterol reduce the risk of allergic rhinitis
This study was published in the Journal of the American College of Nutrition 2007 Jun;26(3):279-87Study title and authors:Fish and fat intake and prevalence of allergic rhinitis in Japanese females: the Osaka Maternal and Child Health Study.Miyake Y, Sasaki S, Tanaka K, Ohya Y, Miyamoto S, Matsunaga I, Yoshida T, Hirota Y, Oda H; Osaka Maternal and Child Health Study Group.Department of Public Health, Fukuoka University, Fukuoka, Japan. miyake-y@cis.fukuoka-u.ac.jpThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17634174The study investigated the association of intake...
Monday, 18 June 2012
Low cholesterol is associated with an increase in death rates in people aged 20 and over
This study was published in Circulation 1997 Sep 2;96(5):1408-15Study title and authors:Serum cholesterol and mortality rates in a Native American population with low cholesterol concentrations: a U-shaped association.Fagot-Campagna A, Hanson RL, Narayan KM, Sievers ML, Pettitt DJ, Nelson RG, Knowler WC.National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Ariz 85014, USA. fax@cu.nih.govThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9315525The study investigated the relationship between cholesterol levels and death rates. The study included 4,553 Pima Indians...
Low saturated fat levels associated with higher suicide rates
This study was published in the Journal of Clinical Psychiatry 2011 Dec;72(12):1585-90Study title and authors:Suicide deaths of active-duty US military and ω-3 fatty-acid status: a case-control comparison.Lewis MD, Hibbeln JR, Johnson JE, Lin YH, Hyun DY, Loewke JD.Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences Bethesda, Maryland, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21903029The study analysed the effects of levels of fats and the risk of suicide. The study included 800 US military suicide deaths and...
Saturday, 16 June 2012
High levels of LDL cholesterol are associated with lower death rates and lower rates of cardiovascular disease
This study was published in the Journal of the American Geriatrics Society 2005 Dec;53(12):2159-64Study title and authors:Low-density lipoprotein cholesterol and mortality in older people.Tikhonoff V, Casiglia E, Mazza A, Scarpa R, Thijs L, Pessina AC, Staessen JA.Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16398902The objective of the study was to investigate the role of low-density lipoprotein (LDL) cholesterol as a predictor of mortality in elderly subjects. The study included 3,120...
Hepatitis C associated with low cholesterol levels
This study was published in the Journal of Viral Hepatitis 2006 Jan;13(1):56-61Study title and authors:Serum lipid pattern in chronic hepatitis C: histological and virological correlations.Siagris D, Christofidou M, Theocharis GJ, Pagoni N, Papadimitriou C, Lekkou A, Thomopoulos K, Starakis I, Tsamandas AC, Labropoulou-Karatza C.Department of Internal Medicine, Patras University Hospital, Patras, Greece. dsiagris@mland.grThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16364083The study investigated the association of cholesterol levels with the hepatitis C virus. The study...
Thursday, 14 June 2012
High cholesterol results in a 13% lower death rate compared to low cholesterol in 35 to 64 year olds
This study was published in the British Medical Journal 1991 Aug 3;303(6797):276-82Study title and authors:Serum cholesterol concentration and coronary heart disease in population with low cholesterol concentrations.Chen Z, Peto R, Collins R, MacMahon S, Lu J, Li W.Medical Research Council and Imperial Cancer Research Fund, Nuffield Department of Clinical Medicine, University of Oxford, Radcliffe Infirmary.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1888927The objective of the study was to examine the relationship between cholesterol levels and death rates. The study included...
Wednesday, 13 June 2012
Low consumption of meat linked to suicide risk
This study was published in Psychiatry Research 2009 Jan 30;165(1-2):111-9Study title and authors:Cross-sectional assessment of diet quality in individuals with a lifetime history of attempted suicide.Li Y, Zhang J, McKeown RE.Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19046606The objective of the study was to describe the differences in food consumption between suicide attempters and non-attempters. Dietary information was analysed from 6803 adults,...
Tuesday, 12 June 2012
The unintended adverse effects of statins in men and women
This study was published in the British Medical Journal 2010 May 20;340:c2197Study title and authors:Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database.Hippisley-Cox J, Coupland C.Division of Primary Care, University Park, Nottingham NG2 7RD. julia.hippisley-cox@ntlworld.comThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20488911The objective of the study was to quantify the unintended effects of statins. The study included 2,004 692 patients aged 30-84 years.The study found after five years:(a) Women...
Monday, 11 June 2012
Diets high in saturated fat reduce the risk of esophageal cancer by 73%
This study was published in the International Journal of Cancer 1999 Jul 2;82(1):33-7Study title and authors:Meat intake and risk of squamous cell esophageal cancer: a case-control study in Uruguay.De Stefani E, Deneo-Pellegrini H, Boffetta P, Mendilaharsu M.Registro Nacional de Cancer, Montevideo, Uruguay.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10360817The study examined the relationship between meat and fat and squamous cell cancer of the esophagus (cancer that begins in flat cells lining the esophagus). The study included 82 cases with esophageal cancer and...
Sunday, 10 June 2012
Low cholesterol levels are linked to an earlier death
Choose DestinationFileClipboardCollectionsE-mailOrderMy BibliographyCitation managerFormatSummary (text)Abstract (text)MEDLINEXMLPMID ListCSVCreate File1 selected item: 12860577FormatSummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListMeSH and Other DataE-mailSubjectAdditional textE-mail"SPAM" filtering software noticeAdd to ClipboardAdd to CollectionsOrder articlesAdd to My BibliographyGenerate a file for use with external citation management software.Create FileThis study was published in the Archives of Internal Medicine 2003 Jul 14;163(13):1549-54Study title and authors:High-density...
Saturday, 9 June 2012
Low-fat diets are inadequate in providing essential vitamins
This study was published in Pediatrics 1992 Feb;89(2):221-8Study title and authors:Nutrient adequacy of low fat intakes for children: the Bogalusa Heart Study.Nicklas TA, Webber LS, Koschak M, Berenson GS.Department of Medicine, Louisiana State University Medical Center, New Orleans 70112.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1734388Professor Theresa Nicklas specializes in how eating behaviours influence the development of chronic disease risk factors early in life. She states that nutritional adequacy is important when diets and dietary alterations are recommended...
Friday, 8 June 2012
Low cholesterol is associated with higher death rates in men
This study was published in the Archives of Internal Medicine 1991 May;151(5):969-72Study title and authors:Serum cholesterol and mortality among Japanese-American men. The Honolulu (Hawaii) Heart Program.Stemmermann GN, Chyou PH, Kagan A, Nomura AM, Yano K.Japan-Hawaii Cancer Study, Honolulu 96817.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2025146This 18 year study examined the association of cholesterol levels with death rates. The study included 7,961 men who were aged between 46 to 65 at the start of the study.The study found that men with cholesterol levels below...
Thursday, 7 June 2012
Saturated fat and dietary cholesterol protect against alcoholic liver cirrhosis
This study was published in Alcoholism, Clinical and Experimental Research 1986 Jun;10(3):271-3Study title and authors:Dietary factors and alcoholic cirrhosis.Nanji AA, French SW.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/3526949Nanji notes that death rates from alcoholic liver cirrhosis in many countries deviate markedly from that expected for a given per capita alcohol intake. This study investigated the possibility that dietary factors might explain the deviation from expected and actual mortality rates in different countries. Data was gathered from 17 countries.The...
Wednesday, 6 June 2012
Statins cause adverse side effects in the oral cavity
This study was published in Medicina Oral, Patologia Oral y Cirugia Bucal 2008 Feb 1;13(2):E98-101Study title and authors:Adverse side effects of statins in the oral cavity.Pascual Cruz M, Chimenos Küstner E, García Vicente JA, Mezquiriz Ferrero X, Borrell Thio E, López López J.Médico estomatólogo, ABS (Area Básica de Salud) Sant Roc Badalona, Facultad de Medicina UAB, Spain. 20673mpc@comb.esThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18223537The objective of the study was to analyze the side effects of statins in the mouth cavity, and to analyze the symptoms after interruption...
Low cholesterol levels are linked to rheumatoid arthritis
This study was published in Arthritis and Rheumatism 2001 Dec;44(12):2761-7Study title and authors:Elevated levels of small, low-density lipoprotein with high affinity for arterial matrix components in patients with rheumatoid arthritis: possible contribution of phospholipase A2 to this atherogenic profile.Hurt-Camejo E, Paredes S, Masana L, Camejo G, Sartipy P, Rosengren B, Pedreno J, Vallve JC, Benito P, Wiklund O.Göteborg University, Sweden. Eva.Hurt-Camejo@astrazeneca.comThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11762936Hurt-Camejo notes that increased death rates...
Tuesday, 5 June 2012
Childhood obesity rates triple as saturated fat consumption declines and grain consumption soars: Can anyone join the dots?
This study was published in the Archives of Disease in Childhood 2000 Jul;83(1):18-24 Study title and authors:US adolescent food intake trends from 1965 to 1996. Cavadini C, Siega-Riz AM, Popkin BM. Nestle Research Center, Nestec Ltd, Lausanne, Switzerland. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/10868993Chilhood obesity tripled from the 1960's to the 1990's. See figure 1 below.FIGURE 1. Prevalence of obesity among children and adolescents, by age group --- United States, 1963--2008The figure above shows the prevalence of obesity among children and adolescents, by...
Sunday, 3 June 2012
Saturated fat may help to prevent osteoporosis
This study was published in Acta Paediatrica 1995 Apr;84(4):388-92Study title and authors:Dietary calcium, saturated fat, fiber and vitamin C as predictors of forearm cortical and trabecular bone mineral density in healthy children and adolescents.Gunnes M, Lehmann EH.Cecor AS, Haugesund, Norway.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7795347The study investigated the effects of diet (including saturated fat) on bone mineral density of the forearm in 495 healthy children (8-11 years) and adolescents (11-17 years).Low bone mineral density in the forearm is associated...
Saturday, 2 June 2012
Low cholesterol is an independent risk factor for developing gastric cancer
This study was published in the International Journal of Cancer 2008 Feb 15;122(4):909-14 Study title and authors:Impact of serum total cholesterol on the incidence of gastric cancer in a population-based prospective study: the Hisayama study.Asano K, Kubo M, Yonemoto K, Doi Y, Ninomiya T, Tanizaki Y, Arima H, Shirota T, Matsumoto T, Iida M, Kiyohara Y.Department of Environmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. k-asano@intmed2.med.kyushu-u.ac.jpThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17957783This study examined...
Friday, 1 June 2012
Low cholesterol levels are associated with death in patients admitted to hospital
This study was published in the Clinical Investigator 1994 Dec;72(12):939-43Study title and authors:The prognostic value of hypocholesterolemia in hospitalized patients.Windler E, Ewers-Grabow U, Thiery J, Walli A, Seidel D, Greten H.Medizinische Kernklinik und Poliklinik, Universität-Krankenhaus Eppendorf, Hamburg, Germany.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7711423The study examined the relationship between cholesterol levels and death rates in patients admitted to hospital. The study included 85,463 patients and 6,543 healthy control subjects.The study found:(a)...
Eminent doctor says it is time for a full reappraisal of the cholesterol theory
This paper was published in World Review of Nutrition and Dietetics 2009;100:80-9 Study title and author:Disappointing recent cholesterol-lowering drug trials: is it not time for a full reappraisal of the cholesterol theory?de Lorgeril M.Coeur et Nutrition, Université Joseph Fourier-Grenoble 1, CNRS, Laboratoire TIMC-IMAG, UMR 5525, Faculté de Médecine, Grenoble, France. michel.delorgeril@ujf-grenoble.frThis paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19696530Dr Michel de Lorgeril is internationally known for his work on cardiovascular disease. Dr de Lorgeril reviews...
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