This study was published in Epidemiology and Infection 1998 Oct;121(2):335-47Study title and authors:Cohort study of serum total cholesterol and in-hospital incidence of infectious diseases.Iribarren C, Jacobs DR Jr, Sidney S, Claxton AJ, Feingold KR.Kaiser Permanente Division of Research, Oakland, CA 94611, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9825784The study assessed the association between cholesterol levels and the risk of infections (other than respiratory and HIV) requiring hospitalisation. The study included 55,300 men and 65,271 women who were followed...
Monday, 30 April 2012
Sunday, 29 April 2012
Cholesterol supplementation benefits patients with Smith-Lemli-Opitz syndrome
This study was published in the American Journal of Medical Genetics 1997 Jan 31;68(3):305-10Study title and authors:Clinical effects of cholesterol supplementation in six patients with the Smith-Lemli-Opitz syndrome (SLOS)Elias ER, Irons MB, Hurley AD, Tint GS, Salen G.Department of Pediatrics, Tufts-New England Medical Center, Boston, Massachusetts, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9024564Children with the Smith-Lemli-Opitz syndrome have very low cholesterol levels and most are either stillborn or die early because of serious malformations of the central...
Low cholesterol levels are associated with higher death rates from respiratory diseases
This study was published in the International Journal of Epidemiology 1997 Dec;26(6):1191-202Study title and authors:Serum total cholesterol and risk of hospitalization, and death from respiratory disease.Iribarren C, Jacobs DR Jr, Sidney S, Claxton AJ, Gross MD, Sadler M, Blackburn H.Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94611, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9447398The study examined the association of cholesterol levels with respiratory diseases. The study included 48,188 men, 55,276 women, age range 25-89, who were...
Saturday, 28 April 2012
Low fat diets induce unhealthy effects in type two diabetics
This study was published in Diabetes Care 1990 Apr;13(4):446-8Study title and authors:Effects of changing amount of carbohydrate in diet on plasma lipoproteins and apolipoproteins in type II diabetic patients.Rivellese AA, Giacco R, Genovese S, Patti L, Marotta G, Pacioni D, Annuzzi G, Riccardi G.Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, Naples, Italy.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2318105This 15 day study investigated the effects of a low fat diet and a high fat diet on eight nonobese, mildly type...
Thursday, 26 April 2012
Low cholesterol levels predict death in patients with bacteria in the blood
This study was published in the Archives of Family Medicine 1995 Sep;4(9):785-9Study title and authors:Risk factors for the development of bacteremia in nursing home patients.Richardson JP, Hricz L.Department of Family Medicine, University of Maryland School of Medicine, Baltimore, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7647945The study examined the association between cholesterol levels and death rates in people with bacteremia (bacteremia is the presence of bacteria in the blood). The study included 26 patients who were admitted into a nursing home.The...
Low fat, low cholesterol diets result in lower cholesterol levels and a higher death rate
This study was published in Advances in Experimental Medicine and Biology 1978;109:317-30Study title and authors:Low fat, low cholesterol diet in secondary prevention of coronary heart disease.Woodhill JM, Palmer AJ, Leelarthaepin B, McGilchrist C, Blacket RB.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/727035The study set out to determine the effects of a low fat, low cholesterol diet on death rates in men with existing heart disease. The study included 458 men, aged 30 to 59, who were followed for up to seven years. The men were allocated in groups to consume...
Tuesday, 24 April 2012
Analysis of six trials show that as cholesterol levels are lowered the death rate increases
This study was published in the British Medical Journal 1990 Aug 11;301(6747):309-14Study title and authors:Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials.Muldoon MF, Manuck SB, Matthews KA.Department of Medicine, University of Pittsburgh, PA 15260.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2144195This study analysed the findings of six cholesterol reduction trials. The participants in the six cholesterol reduction trials received either diet based, drug based, a mixture of diet and drug cholesterol lowering...
Monday, 23 April 2012
High-fat, low-carbohydrate diets are a feasible long-term treatment for type 1 diabetes
This study was published in Upsala Journal of Medical Science 2005;110(3):267-73Study title and authors:A low carbohydrate diet in type 1 diabetes: clinical experience--a brief report.Nielsen JV, Jönsson E, Ivarsson A.Department of Medicine, Blekingesjukhuset, Karlshamn, Sweden. jorgen.vesti-nielsen@ltblekinge.seThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16454166This study examined the effects of a high-fat, low-carbohydrate, diet on 22 patients with type I diabetes who were failing to control fluctuations in their blood sugar levels in higher carbohydrate diets....
Sunday, 22 April 2012
Higher cholesterol levels and higher meat consumption are associated with decreased rates of heart disease deaths
This study was published in the Journal of Internal Medicine 1995 Jan;237(1):49-54 Study title and authors:High serum alpha-tocopherol, albumin, selenium and cholesterol, and low mortality from coronary heart disease in northern Finland.Luoma PV, Näyhä S, Sikkilä K, Hassi J.Oulu Regional Institute of Occupational Health, University of Oulu, Finland. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7830030The study investigated the risk factors for, and the rates of heart disease deaths in northernmost Finland compared with southern areas of Finland. The study...
Saturday, 21 April 2012
Low HDL cholesterol levels are associated with increases in deaths from heart disease and cancer
This study was published in Arteriosclerosis 1988 Nov-Dec;8(6):737-41Study title and authors:High density lipoprotein cholesterol and mortality. The Framingham Heart Study.Wilson PW, Abbott RD, Castelli WP.Framingham Epidemiology Research Section, NHLBI, Massachusetts.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/3196218This 12 year study examined the association of high density lipoprotein (HDL) cholesterol levels with death rates from heart disease and cancer. The study included 2,748 participants aged 50 to 79.The study found:(a) Both men and women with the highest...
Friday, 20 April 2012
Higher cholesterol levels lead to a longer life
This study was published in the Journal of Gerontology 1993 May;48(3):M103-7 Study title and authors:Morbidity and mortality in rural community-dwelling elderly with low total serum cholesterol.Ives DG, Bonino P, Traven ND, Kuller LH.Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed?term=8482813The objective of this two year study was to examine the association of cholesterol levels with death rates in the elderly. The study included 3,874 participants aged 65 to 79....
Thursday, 19 April 2012
Low cholesterol levels are associated with higher rates of dementia
This study was published in the Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2010 May;65(5):559-64Study title and authors:Relationship between low levels of high-density lipoprotein cholesterol and dementia in the elderly. The InChianti study.Zuliani G, Cavalieri M, Galvani M, Volpato S, Cherubini A, Bandinelli S, Corsi AM, Lauretani F, Guralnik JM, Fellin R, Ferrucci L.Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy. gzuliani@hotmail.comThis...
Low cholesterol levels lead to significantly higher death rates
This study was published in the Journal of the American Geriatrics Society 2001 Sep;49(9):1142-7 Study title and authors:The value of serum albumin and high-density lipoprotein cholesterol in defining mortality risk in older persons with low serum cholesterol.Volpato S, Leveille SG, Corti MC, Harris TB, Guralnik JM.Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA. This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11559371The objective of the study was to investigate the relationship between low cholesterol,...
Tuesday, 17 April 2012
High consumption of soft drinks increases the risk of heart disease and diabetes
This study was published in Circulation 2007 Jul 31;116(5):480-8Study title and authors:Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D'Agostino RB, Gaziano JM, Vasan RS.Framingham Heart Study, 73 Mount Wayte Ave, Suite 2, Framingham, MA 01702-5803, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17646581Metabolic syndrome is the name for a group of risk factors that...
Low carbohydrate diets improve blood glucose control in patients with Maturity Onset Diabetes of the Young.
This study was published in the Journal of International Medical Research 2011;39(6):2296-301Study title and authors:The Influence of Dietary Carbohydrate Content on Glycaemia in Patients with Glucokinase Maturity-onset Diabetes of the Young.Klupa T, Solecka I, Nowak N, Szopa M, Kiec-Wilk B, Skupien J, Trybul I, Matejko B, Mlynarski W, Malecki MT.Department of Metabolic Diseases, Jagiellonian University Medical College, Krakow, Poland; Krakow University Hospital, Krakow, Poland.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22289546Maturity...
Monday, 16 April 2012
Statins and fibrates increase the risk of Parkinson's
This study was published in Drug Safety 2008;31(5):399-407Study title and authors:Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK.Becker C, Jick SS, Meier CR.Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18422380This study set out to explore the risk of the development of Parkinson's disease in people with untreated high cholesterol and with people treated with statins and fibrates....
Sunday, 15 April 2012
Adverse side effects may stop up to 75% of patients from continuing with statin treatment
This study was published in the Journal of the American Medical Association 2002 Jul 24-31;288(4):462-7Study title and authors:Adherence with statin therapy in elderly patients with and without acute coronary syndromes.Jackevicius CA, Mamdani M, Tu JV.Department of Health Policy, Management, and Evaluation, Pharmacy Department and Women's Health Program, University Health Network-Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4. Cynthia.Jackevicius@uhn.on.caThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12132976This study was designed to...
Friday, 13 April 2012
High HDL cholesterol gives protection from lung cancer.
This study was published in Lung Cancer 2008 Sep;61(3):292-300Study title and authors:HDL-cholesterol and the incidence of lung cancer in the Atherosclerosis Risk in Communities (ARIC) study.Kucharska-Newton AM, Rosamond WD, Schroeder JC, McNeill AM, Coresh J, Folsom AR; Members of the Atherosclerosis Risk in Communities Study.Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, NC 27514, United States. Anna Newton@unc.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18342390This 13 year study examined the association of...
Low cholesterol linked to an increased risk of suicide
This study was published in Psychiatry Research 2011 Jun 30;188(1):83-7 Study title and author:Low cholesterol is a risk factor for attentional impulsivity in patients with mood symptoms.Troisi A.Department of Neurosciences, University of Rome Tor Vergatta, Rome, Italy. alfonso.troisi@uniroma2.it This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21112642Troisi notes that attentional impulsivity is a demonstrated risk factor for suicide. Attentional impulsivity is related to mania and depression.The study examined the relationship between cholesterol levels and attentional...
Thursday, 12 April 2012
High levels of von Willebrand Factor implicated in diabetes complications - high fat diets lower the levels of von Willebrand Factor
This study was published in Metabolism 1994 Nov;43(11):1406-9Study title and author:Decrease in von Willebrand factor levels after a high-monounsaturated-fat diet in non-insulin-dependent diabetic subjects.Rasmussen O, Thomsen C, Ingerslev J, Hermansen K.Medical Department of M (Diabetes & Endocrinology), Aarhus Kommunehospital, Denmark.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/7526126High levels of von Willebrand factor (a protein used in blood clotting) have been reported in diabetics with cardiovascular complications, suggesting a role for this protein...
Tuesday, 10 April 2012
High fat diets may be beneficial in the treatment of diabetes
This paper was published in Diabetes Care 2009 May;32(5):959-65Study title and authors:Influence of fat and carbohydrate proportions on the metabolic profile in patients with type 2 diabetes: a meta-analysis.Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Sato M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H.Department of Lifestyle Medicine and Applied Nutrition, Ochanomizu University, Tokyo, Japan.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19407076This paper is a meta-analysis of 19 studies which compared the effects of replacing dietary fat with...
Monday, 9 April 2012
Low fat diets increase the risk of heart disease in diabetics
This study was published in the Journal of Clinical Endocrinology and Metabolism 1993 Feb;76(2):347-51Study title and authors:Effect of variations in dietary fat and carbohydrate intake on postprandial lipemia in patients with noninsulin dependent diabetes mellitus.Chen YD, Swami S, Skowronski R, Coulston AM, Reaven GM.Department of Medicine, Stanford University School of Medicine, California.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8432777The effect of dietary composition on concentrations of triglyceride levels was studied in eight...
Higher-fat diets are a more effective treatment for diabetes than low-fat diets
This study was published in Diabetes Research and Clinical Practice 2004 Sep;65(3):235-41Study title and authors:Beneficial effect of low carbohydrate in low calorie diets on visceral fat reduction in type 2 diabetic patients with obesity.Miyashita Y, Koide N, Ohtsuka M, Ozaki H, Itoh Y, Oyama T, Uetake T, Ariga K, Shirai K.Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, School of Medicine, Toho University, 564-1 Shimoshizu, Sakura-City, Chiba 285-0841, Japan.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15331203The aim of this 4 week study was to compare...
Saturday, 7 April 2012
The lower the cholesterol level - the higher the risk of suicide
This study was published in Acta Psychiatrica Scandinavica 2003 Sep;108(3):215-21Study title and authors:Serum lipid levels and suicide attempts.Lee HJ, Kim YK.Department of Psychiatry, Korea University, College of Medicine, Ansan City, Korea.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12890277The objective of the study was to determine whether a correlation exists between lower cholesterol levels and increased suicide risk. Cholesterol levels were measured in 60 patients who had recently experienced failed attempts at suicide and equal numbers of non-suicidal...
High fat/Low carbohydrate diets are particularly effective in reducing the dangerous visceral fat in type II diabetics
This study was published in Diabetes Metabolic Syndrome and Obesity 2011;4:167-74Study title and authors:Effects of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes.Sasakabe T, Haimoto H, Umegaki H, Wakai K.Department of Clinical Nutrition, Haimoto Clinic, Yayoi, Kasugai, Aichi, Japan;This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/21779148Visceral fat refers to the fat that surrounds the internal organs. Subcutaneous fat is body fat that is close to the...
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