Tuesday, 31 January 2012

Slightly more people die on statin treatment

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This study was published in the Lancet 2008 Oct 4;372(9645):1231-9Study title and authors:Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial.Gissi-HF Investigators, Tavazzi L, Maggioni AP, Marchioli R, Barlera S, Franzosi MG, Latini R, Lucci D, Nicolosi GL, Porcu M, Tognoni G.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18757089?dopt=AbstractThe study investigated the effects of the statin rosuvastatin in patients with heart failure. 4,574  patients aged 18 years or older...
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Monday, 30 January 2012

Analysis of 13 studies reveals a high fat intake reduces colon cancer by 8%

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This paper was published in Cancer Causes and Control 1997 Mar;8(2):215-28Study title and authors:The relationship between dietary fat intake and risk of colorectal cancer: evidence from the combined analysis of 13 case-control studies.Howe GR, Aronson KJ, Benito E, Castelleto R, Cornée J, Duffy S, Gallagher RP, Iscovich JM, Deng-ao J, Division of Epidemiology, Columbia University School of Public Health, New York, New York 10032, USA.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9134246The objective of the study was to examine the effects of the intake of dietary...
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Sunday, 29 January 2012

HDL cholesterol levels are 43% higher in healthy people compared to patients with gastric cancer

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This study was published in Hepato-gastroenterology 2003 Dec;50 Suppl 2:cclxxiii-cclxxv.Study title and authors:Serum paraoxonase levels in gastric cancer.Akçay MN, Yilmaz I, Polat MF, Akçay G.Ataturk University Medical Faculty, Department of General Surgery, Erzurum, Turkey.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/15244199High density lipoprotein (HDL) cholesterol levels were measured in 20 patients with gastric cancer and in 20 age-and gender-matched healthy controls.The study found that HDL cholesterol levels were 43% higher in healthy people...
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Saturday, 28 January 2012

Reducing carbohydrate consumption may help to prevent cancer

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This paper was published in Nutrition and Metabolism 2011 Oct 26;8(1):75Study title and authors:Is there a role for carbohydrate restriction in the treatment and prevention of cancer?Klement RJ, Kammerer U.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22029671Dr. Rainer J Klement from the University Hospital of Wurzburg reviewed the evidence of 162 scientific papers regarding the subject of carbohydrate restriction and cancer.Dr. Klement found:Cancer, which might be considered a disease of civilization, was very rare among uncivilized hunter-gatherer...
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Friday, 27 January 2012

Meat and eggs give protection from breast cancer

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This study was published in the Journal of the National Cancer Institute 2003 Mar 5;95(5):373-80Study title and authors:Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.Zhang SM, Willett WC, Selhub J, Hunter DJ, Giovannucci EL, Holmes MD, Colditz GA, Hankinson SE.Department of Epidemiology, Harvard School of Public Health, Division of Preventive Medicine, Boston, MA 02115, USA. Shumin.Zhang@channing.harvard.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed?term=12618502The study investigated the association between vitamins B12 and B6...
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Thursday, 26 January 2012

Statins double the risk of stroke

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This study was published in the New England Journal of Medicine 2005 Jul 21;353(3):238-48Study title and authors:Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis.Wanner C, Krane V, März W, Olschewski M, Mann JF, Ruf G, Ritz E; German Diabetes and Dialysis Study Investigators.Division of Nephrology, Department of Medicine, University of Würzburg, Würzburg, Germany. wanner_c@medizin.uni-wuerzburg.deThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16034009?dopt=AbstractThis study investigated the effects of statin (atorvastatin) treatment...
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Wednesday, 25 January 2012

High amounts of dietary red meat, eggs and fat are associated with decreased rates of pancreatic cancer

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This study was published in Cancer Epidemiology Biomarkers and Prevention 1995 Dec;4(8):885-93Study title and authors:Dietary factors and the risk of pancreatic cancer: a case-control study in Shanghai China.Ji BT, Chow WH, Gridley G, Mclaughlin JK, Dai Q, Wacholder S, Hatch MC, Gao YT, Fraumeni JF Jr.Division of Epidemiology Columbia University, School of Public Health, New York, New York 10032, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/8634662This study examined the effects of diet on pancreatic cancer. The study included 451 people with pancreatic...
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Tuesday, 24 January 2012

High carbohydrate diets increase pancreatic cancer rates

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This study was published in the Journal of the National Cancer Institute 2002 Sep 4;94(17):1293-300Study title and authors:Dietary sugar, glycemic load, and pancreatic cancer risk in a prospective study.Michaud DS, Liu S, Giovannucci E, Willett WC, Colditz GA, Fuchs CS.Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA. michaudd@mail.nih.govThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12208894The study investigated whether diets high in foods that increase after meal glucose levels are...
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Monday, 23 January 2012

Diets high in red meat and saturated fat decrease the incidence of pancreatic cancer

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This study was published in the American Journal of Epidemiology 2003 Jun 15;157(12):1115-25Study title and authors:Dietary meat, dairy products, fat, and cholesterol and pancreatic cancer risk in a prospective study.Michaud DS, Giovannucci E, Willett WC, Colditz GA, Fuchs CS.Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. michaudd@mail.nih.govThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/12796048This study, of 4 years, examined the relationship of diet and the risk...
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Sunday, 22 January 2012

Margarine increases prostate cancer by 30%

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This study was published in Cancer Causes and Control 2004 Feb;15(1):11-20Study title and authors:Foods, nutrients and prostate cancer.Hodge AM, English DR, McCredie MR, Severi G, Boyle P, Hopper JL, Giles GG.Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/14970730This study compared the risk of prostate cancer with margarine consumption in 858 men aged under 70 with prostate cancer and 905 men free from cancer.The study found that higher margarine consumption was associated with an increase...
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Friday, 20 January 2012

Statins increase aggression in women

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This study was published in the Journal of Womens Health 2008 Mar;17(2):187-94Study title and authors:Lipid-lowering medication use and aggression scores in women: a report from the NHLBI-sponsored WISE study.Olson MB, Kelsey SF, Matthews KA, Bairey Merz CN, Eteiba W, McGorray SP, Cornell CE, Vido DA, Muldoon MF.Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/18321170The aim of this study was to examine the association between the use of cholesterol lowering medication and aggression....
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High margarine consumption is associated with an increased risk of pancreatic cancer

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This study was published in the American Journal of Epidemiology 1986 Dec;124(6):894-902Study title and authors:Diet and pancreatic cancer: a case-control study.Norell SE, Ahlbom A, Erwald R, Jacobson G, Lindberg-Navier I, Olin R, Törnberg B, Wiechel KL.Department of Epidemiology, The National Institute of Environmental Medicine Box 60208, S-104 01 Stockholm, SwedenThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/3776972The study examined the association of pancreatic cancer with margarine and butter. The trial contained 99 people with pancreatic cancer and 301 people...
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Thursday, 19 January 2012

Statins increase the risk of diabetes by 48%

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This study was published in the Archives of Internal Medicine 2012 Jan 10Study title and authors:Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative.Culver AL, Ockene IS, Balasubramanian R, Olendzki BC, Sepavich DM, Wactawski-Wende J, Manson JEDepartment of Medicine, University of Massachusetts Medical School, Worcester;This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22231607This study investigated whether the incidence of diabetes is associated with statin use among postmenopausal women. The trial included 161,808...
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Pork reduces pancreatic cancer risk by 75%

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This study was published in the International Journal of Cancer 2002 Mar 20;98(3):480-2Study title and authors:Lifestyle factors and pancreatic cancer risk: a cohort study from the Swedish Twin Registry.Isaksson B, Jonsson F, Pedersen NL, Larsson J, Feychting M, Permert J.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11920604This study of 12,204 female and 9,680 male twins examined the effect of pork consumption on the incidence of pancreatic cancer.The study found that those who consumed the most pork had a 75% reduced risk of pancreatic canc...
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Tuesday, 17 January 2012

Bread and cereals increase the risk of colon cancer by 69%

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This study was published in the International Journal of Cancer 1997 Jul 3;72(1):56-61Study title and authors:Food groups and risk of colorectal cancer in Italy.Franceschi S, Favero A, La Vecchia C, Negri E, Conti E, Montella M, Giacosa A, Nanni O, Decarli A.Servizio di Epidemiologia, Centro di Riferimento Oncologico, Aviano (PN), Italy. franceschis@ets.itThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/9212223This study investigated the influence of various food groups on the risk of colon cancer. The dietary habits of  1,953 subjects with colon cancer and...
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Monday, 16 January 2012

High carbohydrate diets lead to a significant increase in colon cancer

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This study was published in Cancer Epidemiology Biomarkers and Prevention 2002 Feb;11(2):187-93Study title and authors:Carbohydrates and colorectal cancer risk among Chinese in North America.Borugian MJ, Sheps SB, Whittemore AS, Wu AH, Potter JD, Gallagher RP.Cancer Control Research, British Columbia Cancer Agency, Vancouver, British Columbia, V5Z 4E6 Canada. mborugia@bccancer.bc.caThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11867506This study investigated the association between carbohydrate consumption and colon cancer. The study contained 473 people with colon...
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Saturday, 14 January 2012

A higher fat diet reduces colon cancer by 8% compared to a low fat diet

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This study was published in the Journal of the American Medical Association 2006 Feb 8;295(6):643-54Study title and authors:Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial.Beresford SA, Johnson KC, Ritenbaugh C, Lasser NL, Snetselaar LGDepartment of Epidemiology, University of Washington, Seattle, WA 98195-7236, USA. beresfrd@u.washington.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16467233The aim of the study was to evaluate the effects of a low-fat eating pattern on risk of...
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Research by a Nobel prize winner shows that high carbohydrate diets cause cancer

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This paper was published in Science 24 February 1956: Vol. 123 no. 3191 pp. 309-314Study title and author:On the origin of cancer cellsWarburg OThis paper can be accessed at: http://www.sciencemag.org/content/123/3191/309.extractOtto Warburg won the Nobel prize for medicine in 1931 for discovering that cancer cells are fundamentally different compared to healthy cells.He found that energy and growth in cancer cells is mainly generated...
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Thursday, 12 January 2012

High levels of HDL cholesterol are associated with lower levels of breast cancer

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This study was published in Cancer Causes and Control 1992 Sep;3(5):403-8Study title and authors:Serum lipids and breast cancer risk: a cohort study of 5,207 Danish women.Høyer AP, Engholm G.Danish Cancer Registry, Copenhagen.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1525320The association between high density lipoprotein (HDL) cholesterol, triglyceride levels and breast cancer risk was investigated in  5,207 Danish women, aged 30 - 80 over a 26 year period.The study found:(a) Higher triglyceride levels were associated with higher breast cancer...
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Wednesday, 11 January 2012

Low cholesterol increases cancer rates by 42%

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This study was published in the Annals of Oncology 2009 Jun;20(6):1113-20Study title and authors:Time-dependent association of total serum cholesterol and cancer incidence in a cohort of 172,210 men and women: a prospective 19-year follow-up study.Strasak AM, Pfeiffer RM, Brant LJ, Rapp K, Hilbe W, Oberaigner W, Lang S, Borena W, Concin H, Diem G, Ruttmann E, Glodny B, Pfeiffer KP, Ulmer H; VHM&PP Study Group.Department of Medical Statistics, Informatics and Health Economics, Innsbruck Medical University, Innsbruck, Austria. alexander.strasak@i-med.ac.atThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19164459The...
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Tuesday, 10 January 2012

Statins increase lymphoid malignancy rates by 124%

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This study was published in Cancer Science 2006 Feb;97(2):133-8Study title and authors:Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.Iwata H, Matsuo K, Hara S, Takeuchi K, Aoyama T, Murashige N, Kanda Y, Mori S, Suzuki R, Tachibana S, Yamane M, Odawara M, Mutou Y, Kami M.Department of Cardiology, Toranomon Hospital, Tokyo 105-8470, Japan.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/16441424The study examined the association between statin use and development of lymphoid malignancies. Statin use of 221...
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Ladies: No need to feign a headache - just give your man a statin!

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This study was published in Drug Safety 2009;32(7):591-7Study title and authors:Statins and erectile dysfunction: results of a case/non-case study using the French Pharmacovigilance System Database.Do C, Huyghe E, Lapeyre-Mestre M, Montastruc JL, Bagheri H.Université de Toulouse, UPS, Unité de Pharmacoépidémiologie EA 3696, Toulouse, France.This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19530745The object of this study was to investigate the association between exposure to drugs such as statins and the occurrence of erectile dysfunction. Over a 20 year...
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Monday, 9 January 2012

Analysis of 13 studies finds that statins offer no health benefits for women

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This paper was published in the Journal of the American Medical Association 2004;291(18):2243-2252Study title and authors:Drug Treatment of Hyperlipidemia in WomenJudith M. E. Walsh, MD, MPH;Michael Pignone, MD, MPHDivision of General Internal Medicine and Department of Epidemiology and Biostatistics, University of California, San Francisco.This paper can be accessed at: http://jama.ama-assn.org/content/291/18/2243.abstractThe aim of this analysis of 13 studies (which included 19,707 women) was to determine if cholesterol lowering drugs such as statins have any effect on heart disease...
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Statins cause a massive rise in constipation

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This study was published in the Journal of the American Medical Directors Association 2010 Oct;11(8):572-8Study title and authors:Risk factors associated with stool retention assessed by abdominal radiography for constipation.Gau JT, Walston S, Finamore M, Varacallo CP, Heh V, Kao TC, Heckman TG.Department of Geriatric Medicine/Gerontology, Ohio University College of Osteopathic Medicine (OU-COM), Athens, OH 45701, USA. gau@oucom.ohiou.eduThis study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/20889093One of the aims of the study was to identify risk factors associated with constipation....
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JUPITER statin trial a biased sham

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This paper was published in the Archives of Internal Medicine 2010;170(12):1032-1036Study title and authors:Cholesterol Lowering, Cardiovascular Diseases, and the Rosuvastatin-JUPITER ControversyA Critical Reappraisal Michel de Lorgeril, MD; Patricia Salen, BSc; John Abramson, MD; Sylvie Dodin, MD; Tomohito Hamazaki, PhD; Willy Kostucki, MD; Harumi Okuyama, PhD; Bruno Pavy, MD; Mikael Rabaeus, MDThis paper can be accessed at: http://archinte.ama-assn.org/cgi/content/full/170/12/1032#REF-IOI05093-1Dr. de Lorgeril notes that the results of cholesterol-lowering drug trials...
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Sunday, 8 January 2012

Statins offer no benefit to the elderly

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This study was published in the Lancet 2002 Nov 23;360(9346):1623-30Study title and authors:Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Meinders AE, Norrie J, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG; PROSPER study group. PROspective Study of Pravastatin in the Elderly at Risk.University Department of Pathological Biochemistry, University of Glasgow, Royal Infirmary, Scotland,...
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Friday, 6 January 2012

High fat diets reduce dangerous C-reactive protein levels by 52.6%

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This study was published in Diabetologia 2005 Jan;48(1):8-16Study title and authors:Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women.McAuley KA, Hopkins CM, Smith KJ, McLay RT, Williams SM, Taylor RW, Mann JIEdgar National Centre for Diabetes Research, Medical and Surgical Sciences, University of Otago, PO Box 56, Dunedin, New Zealand. kirsten.mcauley@stonebow.otago.ac.nzThis study can be accessed at: http://www.springerlink.com/content/1abv5hablr8veyrm/fulltext.htmlHigh levels of C-reactive protein and triglycerides are associated...
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Tuesday, 3 January 2012

Professor says the cholesterol hypothesis is false and should be buried

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This paper was published in the Scandinavian Cardiovascual Journal 2011 Dec;45(6):322-3Study title and author:The cholesterol hypothesis: time for the obituary?Scherstén T, Rosch PJ, Arfors KE, Sundberg R.This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22070401Dr. Schersten is a professor of Vascular Surgery, University of Göteborg and was previously Principal Secretary of the Swedish Medical Research Council.Professor Schersten finds that the cholesterol hypothesis that links cholesterol intake and blood cholesterol levels to cardiovascular disease has little or no scientific...
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